Document Detail

Integrated monitoring of a new group B streptococcal disease prevention program and other perinatal infections.
MedLine Citation:
PMID:  12092979     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine levels of prenatal screening for several infections, intrapartum recognition of risk factors, and prophylaxis against mother-to-child transmission of group B streptococcus. METHODS: Review of stratified random sample of hospital records for deliveries in Connecticut during 1996. SUDAAN analysis was used to adjust for the complex survey design, and weighting adjusted for the probability of being sampled and nonresponse. RESULTS: Of 992 records requested, 868 (88%) were abstracted and analyzed. Thirty-six percent of women had prenatal screening for group B streptococcus and 26% had been tested for human immunodeficiency virus (HIV), while 97-99% of women had been screened prenatally for hepatitis B surface antigen, rubella, and syphilis. Of those women tested, 17% were detected as group B streptococcus carriers, and 78% of these received intrapartum antibiotic prophylaxis. Among women who were not screened for group B streptococcus prenatally, 22% met risk-based criteria for prophylaxis, but only 45% of these received intrapartum prophylaxis. Among unscreened women with a risk factor, those with shorter hospital stays prior to delivery, admitted on evening or night shifts, or who delivered on the weekend were significantly less likely to receive intrapartum prophylaxis. CONCLUSION: In 1996, the majority of women who delivered in Connecticut were not tested prenatally for group B streptococcus and the majority of those not tested in whom there was an indication for prophylaxis were not treated. Compliance with group B streptococcus prevention recommendations can be improved through increased prenatal testing and/or better recognition of risk-based criteria for intrapartum prophylaxis.
Anne Schuchat; Aaron Roome; Elizabeth R Zell; Heather Linardos; Sara Zywicki; Katherine L O'Brien
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Maternal and child health journal     Volume:  6     ISSN:  1092-7875     ISO Abbreviation:  Matern Child Health J     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-07-02     Completed Date:  2002-12-23     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9715672     Medline TA:  Matern Child Health J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  107-14     Citation Subset:  IM    
Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
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MeSH Terms
Anti-Bacterial Agents / therapeutic use
Infant, Newborn
Infectious Disease Transmission, Vertical / prevention & control*
Pregnancy Complications, Infectious / diagnosis,  drug therapy,  prevention & control*
Prenatal Diagnosis / utilization*
Streptococcal Infections / diagnosis,  drug therapy,  microbiology,  prevention & control*,  transmission
Streptococcus agalactiae / isolation & purification*
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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