Document Detail

Integrated excitatory response to microinjections of L-glutamic acid into the reticular system of the toad.
MedLine Citation:
PMID:  607228     Owner:  NLM     Status:  MEDLINE    
Microinjections of L-glutamic acid into the mesencephalic tegmentum and diencephalon of anesthetized toads evoked an excitatory response consisting of electrocephalographic and electromyographic activation, and a rise in arterial blood pressure. Electromyographic responses were reduced or absent in diencephalically injected toads. Except for this case, all other components of the response always appeared together and presented the same time course. L-glutamic acid was able to activate a group of neurons at different levels of the reticular system involved in an integrated response of ergotropic nature.
A Hoffmann; F Costa; M C Lico
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Physiology & behavior     Volume:  19     ISSN:  0031-9384     ISO Abbreviation:  Physiol. Behav.     Publication Date:  1977 Aug 
Date Detail:
Created Date:  1978-04-26     Completed Date:  1978-04-26     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0151504     Medline TA:  Physiol Behav     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  179-83     Citation Subset:  IM    
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MeSH Terms
Blood Pressure / drug effects
Diencephalon / drug effects
Evoked Potentials / drug effects
Glutamates / administration & dosage,  pharmacology*
Neurons / drug effects
Reticular Formation / cytology,  drug effects*
Tegmentum Mesencephali / drug effects
Reg. No./Substance:

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