Document Detail


Integrated Coronary Physiology in Percutaneous Intervention: A new paradigm in interventional cardiology.
MedLine Citation:
PMID:  20884292     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Coronary angiography has provided an unrivalled appreciation of coronary anatomy fostering a far greater appreciation of the extent of atherosclerotic disease. However, the subjectivity of coronary angiography at determining the extent of plaque has been exposed with IVUS. Indices of coronary physiology have provided valuable adjunctive information as to the physiological importance of specific lesions. Fractional flow reserve is an established method for evaluating the significance of epicardial stenoses. Fractional flow reserve guided percutaneous coronary intervention is associated with improved outcomes when compared to a conventional angiographic guided strategy, particularly in intermediate lesions. The use of coronary physiology in the cath lab represents a new avenue to guide appropriate patient specific revascularisation strategies. This review examines the theory and evidence for fractional flow reserve and its use in percutaneous coronary intervention.
Authors:
J Layland; A M Macisaac; A T Burns; R J Whitbourn; A M Wilson
Publication Detail:
Type:  Journal Article     Date:  2010-09-29
Journal Detail:
Title:  Heart, lung & circulation     Volume:  20     ISSN:  1444-2892     ISO Abbreviation:  Heart Lung Circ     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-09-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100963739     Medline TA:  Heart Lung Circ     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  641-6     Citation Subset:  IM    
Copyright Information:
Crown Copyright © 2010. Published by Elsevier B.V. All rights reserved.
Affiliation:
Cardiovascular Research Centre, St. Vincent's Hospital, Melbourne, Victoria, Australia; University of Melbourne, Parkville, Melbourne, Victoria, Australia.
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