Document Detail


Integrated anti-remodeling and anabolic therapy for the osteoporosis of Hajdu-Cheney syndrome.
MedLine Citation:
PMID:  17103298     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hajdu-Cheney syndrome (MIM 102500) is a rare skeletal dysplasia marked by severe generalized osteoporosis and focal bone loss (acro-osteolysis). Osteoporosis treatment outcome has been reported only once previously. Reported herein is the biochemical and densitometric response to integrated anti-remodeling and anabolic therapy in a woman with Hajdu-Cheney syndrome. Results suggest dissociation of bone formation from bone resorption resulting in dramatic increases in bone mineral density without clinical evidence of activated osteoporosis.
Authors:
F E McKiernan
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2006-11-14
Journal Detail:
Title:  Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA     Volume:  18     ISSN:  0937-941X     ISO Abbreviation:  Osteoporos Int     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-01-11     Completed Date:  2007-04-16     Revised Date:  2008-07-18    
Medline Journal Info:
Nlm Unique ID:  9100105     Medline TA:  Osteoporos Int     Country:  England    
Other Details:
Languages:  eng     Pagination:  245-9     Citation Subset:  IM    
Affiliation:
Center for Bone Diseases, Marshfield Clinic, 1000 N. Oak Avenue, Marshfield, WI 54449, USA. mckiernan.fergus@marshfieldclinic.org
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MeSH Terms
Descriptor/Qualifier:
Adult
Bone Density / physiology
Bone Density Conservation Agents / therapeutic use
Bone Remodeling / drug effects,  physiology
Female
Hajdu-Cheney Syndrome / complications,  drug therapy*,  physiopathology
Humans
Osteoporosis / complications,  drug therapy*,  physiopathology
Spinal Fractures / etiology,  physiopathology,  prevention & control
Treatment Outcome
Chemical
Reg. No./Substance:
0/Bone Density Conservation Agents
Comments/Corrections
Comment In:
Osteoporos Int. 2008 Mar;19(3):379-80   [PMID:  17874031 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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