Document Detail


Intake of heterocyclic aromatic amines from meat in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Heidelberg cohort.
MedLine Citation:
PMID:  18309547     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
It was the aim of the present study to estimate the intake of heterocyclic aromatic amines (HCA) from meat, which have been associated with cancer risk in several epidemiological studies, of 21 462 subjects who participated in the European Prospective Investigation into Cancer and Nutrition (EPIC) in Heidelberg. This was accomplished by using a detailed dietary questionnaire that assessed meat consumption, cooking methods, and degree of browning of the respective food items. Median total HCA intake from meat was 31 ng/d (mean 69 ng/d), which was lower than results observed in previous studies. 2-Amino-1-methyl-6-phenylimidazo[4,5b]pyridine was the most common HCA in this cohort (median 17; mean 48 ng/d). The present study offers the opportunity of a detailed examination of the associations between meat cooking as well as HCA intake from meat and cancer risk in a prospective way.
Authors:
Sabine Rohrmann; Dorothee Zoller; Silke Hermann; Jakob Linseisen
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Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The British journal of nutrition     Volume:  98     ISSN:  0007-1145     ISO Abbreviation:  Br. J. Nutr.     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2008-02-27     Completed Date:  2008-03-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372547     Medline TA:  Br J Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  1112-5     Citation Subset:  IM    
Affiliation:
Division of Clinical Epidemiology, German Cancer Research Centre, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. s.rohrmann@dkfz.de
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Distribution
Aged
Amines / analysis*
Cookery
Europe
Female
Heterocyclic Compounds / analysis*
Humans
Male
Meat / analysis*
Middle Aged
Neoplasms / chemically induced*
Nutrition Surveys
Prospective Studies
Risk
Sex Distribution
Socioeconomic Factors
Chemical
Reg. No./Substance:
0/Amines; 0/Heterocyclic Compounds

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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