Document Detail

Intake and gastric emptying of mono- versus disaccharides by rats.
MedLine Citation:
PMID:  3761024     Owner:  NLM     Status:  MEDLINE    
Eating and gastric emptying of mono- versus disaccharides were measured in rats which consumed each day a carbohydrate solution and, 5 h later, a restricted amount of a nutritionally adequate dry diet. When Wistar rats were offered 30% (wt/vol) sugar solutions for 60 min a day, energy intakes were smaller for glucose than for maltose or dextrin and smaller for invert sugar (fructose + glucose) than for sucrose. Sprague-Dawley rats consumed less energy from glucose than maltose when fed 60%, but not 15%, solutions of these sugars. Among Wistar rats accustomed to hypotonic carbohydrate meals, gastric emptying (kilocalories/minute) was slower for 30% glucose than 30% maltose and for 63% maltose than 21% maltose. These differences became obscured with continued exposure to highly hypertonic meals. Monosaccharides, being small, highly soluble molecules, can impart great osmolality to stomach contents. It appears that this osmotic property of monosaccharides tends to slow eating and gastric emptying.
D L Trout; P A Bernstein
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of nutrition     Volume:  116     ISSN:  0022-3166     ISO Abbreviation:  J. Nutr.     Publication Date:  1986 Sep 
Date Detail:
Created Date:  1986-11-21     Completed Date:  1986-11-21     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0404243     Medline TA:  J Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1682-93     Citation Subset:  IM    
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MeSH Terms
Body Weight
Dietary Carbohydrates / metabolism*
Disaccharides / metabolism*
Energy Intake*
Energy Metabolism
Gastric Emptying*
Monosaccharides / metabolism*
Osmolar Concentration
Time Factors
Reg. No./Substance:
0/Dietary Carbohydrates; 0/Disaccharides; 0/Monosaccharides

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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