| Intact survival in extremely low birth weight infants after delivery room resuscitation. | |
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MedLine Citation:
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PMID: 10506265 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: None of the 20 previously reported infants weighing <750 g at birth who received cardiopulmonary resuscitation (CPR) in the delivery room (DR) survived. To clarify whether such resuscitation is futile in our center, we evaluated our experience with DR-CPR over a 4-year period. STUDY DESIGN: We retrospectively reviewed the outcomes of all inborn infants with birth weights <1000 g at University of California, San Diego Medical Center from January 1993 to December 1996. Surviving infants and matched control infants were followed for </=40 months' adjusted age using standardized neurodevelopmental assessments. RESULTS: Of the infants with birth weight <1000 g born during this period, 29% (51/177) died, including 44% of those <750 g and 16% of those >/=750 g. Overall, 19 infants received DR-CPR, of whom 12 were <750 g. Of the infants who received DR-CPR, 79% (15/19) survived, including 10 of 13 infants <750 g and 5 of 6 infants >/=750 g. Of the 15 survivors, 10 were followed beyond 10 months' adjusted age (median: 28 months). At last examination, 70% were both neurologically and developmentally normal. Two infants had cerebral palsy with mild cognitive and severe motor developmental delay. Of 7 infants with birth weight <750 g, 6 had normal neurodevelopmental outcomes. The mean composite mental and motor scores of DR-CPR survivors were 93 +/- 10 and 89 +/- 25, respectively. No differences were found in neurologic or developmental outcome between DR-CPR survivors and control infants matched for gestational age, sex, and year of birth. CONCLUSIONS: Our results indicate that intact survival is possible for infants weighing <750 g at birth after DR-CPR. |
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Authors:
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N N Finer; T Tarin; Y E Vaucher; K Barrington; R Bejar |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pediatrics Volume: 104 ISSN: 1098-4275 ISO Abbreviation: Pediatrics Publication Date: 1999 Oct |
Date Detail:
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Created Date: 1999-10-14 Completed Date: 1999-10-14 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0376422 Medline TA: Pediatrics Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: e40 Citation Subset: IM |
Affiliation:
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Division of Neonatology, Department of Pediatrics, University of California, San Diego, California 92103-8774, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cardiopulmonary Resuscitation* Child Development* Delivery Rooms Developmental Disabilities Epinephrine / therapeutic use Female Gestational Age Humans Infant, Newborn Infant, Small for Gestational Age Infant, Very Low Birth Weight* Male Medical Futility* Neuropsychological Tests Retrospective Studies Survivors |
| Chemical | |
Reg. No./Substance:
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51-43-4/Epinephrine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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