Document Detail


Intact survival in extremely low birth weight infants after delivery room resuscitation.
MedLine Citation:
PMID:  10506265     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: None of the 20 previously reported infants weighing <750 g at birth who received cardiopulmonary resuscitation (CPR) in the delivery room (DR) survived. To clarify whether such resuscitation is futile in our center, we evaluated our experience with DR-CPR over a 4-year period. STUDY DESIGN: We retrospectively reviewed the outcomes of all inborn infants with birth weights <1000 g at University of California, San Diego Medical Center from January 1993 to December 1996. Surviving infants and matched control infants were followed for </=40 months' adjusted age using standardized neurodevelopmental assessments. RESULTS: Of the infants with birth weight <1000 g born during this period, 29% (51/177) died, including 44% of those <750 g and 16% of those >/=750 g. Overall, 19 infants received DR-CPR, of whom 12 were <750 g. Of the infants who received DR-CPR, 79% (15/19) survived, including 10 of 13 infants <750 g and 5 of 6 infants >/=750 g. Of the 15 survivors, 10 were followed beyond 10 months' adjusted age (median: 28 months). At last examination, 70% were both neurologically and developmentally normal. Two infants had cerebral palsy with mild cognitive and severe motor developmental delay. Of 7 infants with birth weight <750 g, 6 had normal neurodevelopmental outcomes. The mean composite mental and motor scores of DR-CPR survivors were 93 +/- 10 and 89 +/- 25, respectively. No differences were found in neurologic or developmental outcome between DR-CPR survivors and control infants matched for gestational age, sex, and year of birth. CONCLUSIONS: Our results indicate that intact survival is possible for infants weighing <750 g at birth after DR-CPR.
Authors:
N N Finer; T Tarin; Y E Vaucher; K Barrington; R Bejar
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatrics     Volume:  104     ISSN:  1098-4275     ISO Abbreviation:  Pediatrics     Publication Date:  1999 Oct 
Date Detail:
Created Date:  1999-10-14     Completed Date:  1999-10-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376422     Medline TA:  Pediatrics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  e40     Citation Subset:  IM    
Affiliation:
Division of Neonatology, Department of Pediatrics, University of California, San Diego, California 92103-8774, USA.
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MeSH Terms
Descriptor/Qualifier:
Cardiopulmonary Resuscitation*
Child Development*
Delivery Rooms
Developmental Disabilities
Epinephrine / therapeutic use
Female
Gestational Age
Humans
Infant, Newborn
Infant, Small for Gestational Age
Infant, Very Low Birth Weight*
Male
Medical Futility*
Neuropsychological Tests
Retrospective Studies
Survivors
Chemical
Reg. No./Substance:
51-43-4/Epinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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