Document Detail

Insulinoma complicating pregnancy presenting with hypoglycemic coma after delivery: a case report and review of the literature.
MedLine Citation:
PMID:  2539573     Owner:  NLM     Status:  MEDLINE    
The incidence of insulinoma in pregnancy is unknown. All of the eight previously reported cases presented in the first trimester with hypoglycemic episodes. We report a case of a 24-year-old multigravida who presented with hypoglycemic coma after delivery. We discuss the possible protective role of pregnancy counter-regulatory hormones in keeping the patient asymptomatic until delivery, and present the difficulties in both diagnosis and differential diagnosis of insulinoma in the peripartum period. Chronic hypoglycemia in pregnancy has been associated with intrauterine growth retardation and increased perinatal mortality. However, this infant was at the 90th percentile for body weight, suggesting that asymptomatic maternal hypoglycemia had not been present during the gestation. Insulinoma complicating pregnancy, though very rare, should now be included in the differential diagnosis of postpartum hypoglycemia.
P R Garner; R Tsang
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  73     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1989 May 
Date Detail:
Created Date:  1989-05-19     Completed Date:  1989-05-19     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  847-9     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, University of Ottawa, Ontario, Canada.
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MeSH Terms
Adenoma, Islet Cell / complications*
Diagnosis, Differential
Hypoglycemia / etiology*
Infant, Newborn
Insulin / blood
Insulin Coma / etiology*
Insulinoma / blood,  complications*,  diagnosis,  surgery
Pancreatic Neoplasms / blood,  complications*,  diagnosis,  surgery
Pregnancy Complications, Neoplastic* / blood,  diagnosis,  surgery
Puerperal Disorders / etiology*
Reg. No./Substance:

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