Document Detail


Insulin resistance influences weight loss in non-obese women who followed a home-based exercise program and slight caloric restriction.
MedLine Citation:
PMID:  21466903     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
This study aimed to evaluate the influence of insulin resistance status on weight changes in non-obese women who followed a home-based exercise program and slight caloric restriction over a period of 12 months. Middle-aged (25-45 year), non-obese (body mass index of 23-29.9kg/m(2)) women were randomly assigned to control (CG) or home-based exercise group (HB). The HB group received a booklet explaining the physical exercises to be practiced at home at least three times per week (40min/session). Both groups were required to follow a small energy restriction of 100-300calories per day. For the analysis, women were stratified in two groups according to baseline insulin sensitivity: NIR (non-insulin resistant; n=121) and IR (insulin resistant; n=64). Women classified as IR at baseline had greater weight loss after 12 months of follow-up (-1.6kg vs. -1.1kg; p=0.01), and HB exercise helped to reduce weight only among NIR women (-1.5 vs. -0.7; p=0.04); no differences were observed between intervention groups for IR women (-1.5 vs. -1.7; p=0.24). There were no differences between IR and NIR groups for lipid profile after adjustment for weight changes. Insulin resistance facilitated weight loss, and home-based exercise promoted greater weight loss only in non-insulin resistance women.
Authors:
Mauro Felippe Felix Mediano; Rosely Sichieri
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-4-3
Journal Detail:
Title:  Diabetes research and clinical practice     Volume:  -     ISSN:  1872-8227     ISO Abbreviation:  -     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-4-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8508335     Medline TA:  Diabetes Res Clin Pract     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Department of Clinical and Experimental Medicine, Rio de Janeiro State University, Rio de Janeiro, Brazil.
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