| Insulin resistance, dyslipidemia, and metabolic syndrome in women with polycystic ovary syndrome. | |
| | |
MedLine Citation:
|
PMID: 20199774 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To investigate the association of insulin resistance with dyslipidemia and metabolic syndrome (MBS) in women with polycystic ovary syndrome (PCOS). METHODS: Fasting glucose (G), insulin (I), and lipid levels were measured in 50 infertile women with PCOS. A fasting G/I ratio of 4.5 or less (n=29) defined insulin resistance (IR). RESULTS: The mean levels of total cholesterol (P<0.001), low-density lipoprotein (P=0.02), and triglycerides (P<0.001) were significantly higher and the mean levels of high-density lipoprotein were significantly lower (P<0.001) in the IR group. The prevalence of MBS (P=0.02) and obesity (P=0.04), hypertension (P=0.02), fasting hyperglycemia (P=0.03), low high-density lipoprotein levels (P=0.02), and hypertriglyceridemia (P=0.02) were also significantly higher in the IR group. CONCLUSION: Insulin resistance is associated with dyslipidemia and MBS in women with PCOS. Lifestyle modification and insulin-sensitizing agents should be part of the management plan. |
| | |
Authors:
|
Akmal El-Mazny; Nermeen Abou-Salem; Walid El-Sherbiny; Ahmed El-Mazny |
Related Documents
:
|
20334584 - The role of chronic inflammation and leu55met pon1 polymorphism in the pathogenesis of ... 15474914 - Increased circulatory dehydroepiandrosterone and dehydroepiandrosterone-sulphate in fir... 9429864 - Polycystic ovary syndrome. 8550794 - Dehydroepiandrosterone, dehydroepiandrosterone sulfate, obesity, waist-hip ratio, and n... 8477874 - Preferential alteration of oxidative relative to total glycolysis in pancreatic islets ... 21557044 - Oxidative stress and diabetic kidney disease. |
Publication Detail:
|
Type: Journal Article Date: 2010-03-02 |
Journal Detail:
|
Title: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics Volume: 109 ISSN: 1879-3479 ISO Abbreviation: Int J Gynaecol Obstet Publication Date: 2010 Jun |
Date Detail:
|
Created Date: 2010-05-07 Completed Date: 2010-08-17 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0210174 Medline TA: Int J Gynaecol Obstet Country: Ireland |
Other Details:
|
Languages: eng Pagination: 239-41 Citation Subset: IM |
Copyright Information:
|
Copyright 2010 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
|
Department of Obstetrics and Gynecology, Faculty of Medicine, Cairo University, Egypt. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Cross-Sectional Studies Dyslipidemias / epidemiology*, etiology Female Glucose / metabolism Humans Hyperglycemia / epidemiology, etiology Hypertension / epidemiology, etiology Insulin / metabolism Insulin Resistance* Lipids / blood Metabolic Syndrome X / epidemiology*, etiology Obesity / epidemiology, etiology Polycystic Ovary Syndrome / physiopathology* Prevalence Risk Factors Young Adult |
| Chemical | |
Reg. No./Substance:
|
0/Lipids; 11061-68-0/Insulin; 50-99-7/Glucose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: DC-expressed MHC class I single-chain trimer-based vaccines prime cytotoxic T lymphocytes against ex...
Next Document: A survey of Russian women regarding the presence of a companion during labor.