| [Insulin pump therapy: indications and risks - Case 7/2010]. | |
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MedLine Citation:
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PMID: 20730708 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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HISTORY, ADMISSION FINDINGS AND TREATMENT: In a 35-year-old pregnant woman (pat. 1) with type 1 diabetes, insulin pump therapy was initiated because of very fluctuating blood glucose levels with severe hypoglycaemias and worsening hypoglycaemia unawareness during pregnancy. In a 45-year-old female (pat. 2) with type 1 diabetes, severe hypoglycemia with loss of consciousness occurred because of dysfunction of the insulin pump and subsequent several-fold application of bolus insulin. After intravenous administration of 40% glucose solution the patient recovered soon and was admitted to hospital for further treatment. COURSE: With CSII blood glucose levels were in patient 1 more stable and HbA (1c) remained within the normal range. The pregnancy proceeded without further complications and the patient gave birth to a healthy boy on time. In patient 2, insulin pump treatment was reinititated after a temporarily change to an intensified conventional insulin regimen and an insulin pump therapy education update. CONCLUSION: The main advantage of an insulin pump therapy is the higher flexibility regarding the basal insulin rate, in particular in patients with highly fluctuating insulin demand during the day and/or hypoglycaemia unawareness. As a disadvantage can be seen the higher costs, especially as superiority of insulin pump therapy compared to intensified conventional treatment could not be shown for all patients. |
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Authors:
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Caroline Ketterer; Karsten Müssig; Anna-Katharina Gerstenecker; Andreas Fritsche |
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Publication Detail:
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Type: Case Reports; English Abstract; Journal Article Date: 2010-08-20 |
Journal Detail:
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Title: Deutsche medizinische Wochenschrift (1946) Volume: 135 ISSN: 1439-4413 ISO Abbreviation: Dtsch. Med. Wochenschr. Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-08-23 Completed Date: 2010-09-15 Revised Date: 2011-08-25 |
Medline Journal Info:
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Nlm Unique ID: 0006723 Medline TA: Dtsch Med Wochenschr Country: Germany |
Other Details:
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Languages: ger Pagination: 1617 Citation Subset: IM |
Copyright Information:
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Georg Thieme Verlag KG Stuttgart * New York. |
Affiliation:
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Medizinische Universitätsklinik Tübingen, Abteilung für Endokrinologie, Diabetologie, Nephrologie, Angiologie und Klinische Chemie, Tübingen. caroline.ketterer@med.uni-tuebingen.de |
Vernacular Title:
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Insulinpumpentherapie: Indikationen und Risiken - Fall 7/2010. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Glucose / metabolism Diabetes Mellitus, Type 1 / blood, drug therapy* Diabetic Coma / blood, chemically induced Equipment Failure* Female Hemoglobin A, Glycosylated / metabolism Humans Hypoglycemia / blood, chemically induced Infant, Newborn Insulin Infusion Systems / adverse effects* Male Middle Aged Pregnancy Pregnancy in Diabetics / blood, drug therapy* Risk Factors |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 0/Hemoglobin A, Glycosylated; 0/hemoglobin A1c protein, human |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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