| Insulin extraction and glucose output by the perfused liver of starved rats. | |
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MedLine Citation:
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PMID: 2694922 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Using the isolated and perfused liver of rats, we investigated the effect of starvation on hepatic glucose output and hepatic insulin extraction. The rats were starved for 72 h. The intestines of fed and starved rats were isolated and perfused, and portal venous effluent (PVE) was collected. The liver of fed and starved rats was perfused with synthetic medium or PVE containing 100 mg/dl glucose and 100 muU/ml insulin. Fractional uptake of insulin and reduction in glucose output by the perfused liver were almost the same in all groups. These results suggest that the removal and action of insulin in the liver were not altered by short-term starvation in rats. |
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Authors:
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T Ikeda; K Fujiyama; T Hoshino; T Takeuchi; H Mashiba; M Tominaga |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Annals of nutrition & metabolism Volume: 33 ISSN: 0250-6807 ISO Abbreviation: Ann. Nutr. Metab. Publication Date: 1989 |
Date Detail:
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Created Date: 1990-02-23 Completed Date: 1990-02-23 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8105511 Medline TA: Ann Nutr Metab Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 354-8 Citation Subset: IM |
Affiliation:
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First Department of Internal Medicine, Tottori University School of Medicine, Yonago, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Glucose / analysis Body Weight Glucose / metabolism* Insulin / blood, metabolism* Liver / metabolism*, pathology Male Organ Size Oxygen Consumption Perfusion Rats Rats, Inbred Strains Starvation / metabolism* |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 11061-68-0/Insulin; 50-99-7/Glucose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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