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Insulin-dependent signaling: regulation by amino acids and energy.
MedLine Citation:
PMID:  20021119     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Recent research has indicated that amino acids stimulate a signal-transduction pathway that is also used by insulin. Moreover, for insulin to exert its anabolic and anticatabolic effects on protein, there is an absolute requirement for amino acids. This signaling pathway becomes inhibited by adenosine monophosphate-activated protein kinase when energy production falls short. In this brief review some of the experimental evidence is discussed.
Authors:
A J Meijer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Toxicology mechanisms and methods     Volume:  14     ISSN:  1537-6524     ISO Abbreviation:  Toxicol. Mech. Methods     Publication Date:  2004  
Date Detail:
Created Date:  2009-12-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101134521     Medline TA:  Toxicol Mech Methods     Country:  England    
Other Details:
Languages:  eng     Pagination:  31-4     Citation Subset:  -    
Affiliation:
Department of Biochemistry, Academic Medical Center, Amsterdam, The Netherlands.
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