| Insufficient acetabular version increases blood metal ion levels after metal-on-metal hip resurfacing. | |
| | |
MedLine Citation:
|
PMID: 21656317 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Many factors affect the blood metal ion levels after metal-on-metal (MOM) hip arthroplasty. The main surgically adjustable variable is the amount of coverage of the head provided by the cup which is a function of the inclination and version angles. However, most studies have used plain radiographs which have questionable precision and accuracy, particularly for version and large diameter metal heads; further, these studies do not simultaneously assess version and inclination. Thus the relationship between version and blood metal ions levels has not been resolved. QUESTIONS/PURPOSES: We determined whether cup inclination and version influence blood metal ion levels while adjusting for age at assessment, gender, body mass index, horizontal femoral offset, head size, manufacturer hip type, and Oxford hip score. PATIENTS AND METHODS: We prospectively followed 100 individuals (51 females, 49 males) with unilateral MOM hip resurfacing who underwent clinical assessment, CT scanning, and blood metal ion measurement. Multiple regression analysis was used to determine which variables were predictors of blood metal ion levels and to model the effect of these variables. RESULTS: Only cup inclination, version angles, and gender influenced blood cobalt or chromium levels. Cobalt and chromium levels positively correlated with inclination angle and negatively correlated with version angle. The effect of changes in version angle was less than for inclination angle. Based on our observations, we developed a formula to predict the effect of these parameters on metal ion levels. CONCLUSIONS: Our data suggest insufficient cup version can cause high blood metal ions after MOM hip arthroplasty. We were unable to show that excessive version caused high levels. LEVEL OF EVIDENCE: Level II, prognostic study. See Guidelines for Authors for a complete description of levels of evidence. |
| | |
Authors:
|
Alister J Hart; John A Skinner; Johann Henckel; Barry Sampson; Fabiana Gordon |
Related Documents
:
|
18451667 - Blood volume monitoring. 8281717 - The influence of dialyzer geometry on blood coagulation and biocompatibility. 12147797 - In vitro and in vivo evaluation of a new dialyzer. 12027137 - Measurements of hemodialysis catheter blood flow in vivo. 8125397 - Gut ischaemia. 21403877 - Dlbs1033, a protein extract from lumbricus rubellus, possesses antithrombotic and throm... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2011-06-09 |
Journal Detail:
|
Title: Clinical orthopaedics and related research Volume: 469 ISSN: 1528-1132 ISO Abbreviation: Clin. Orthop. Relat. Res. Publication Date: 2011 Sep |
Date Detail:
|
Created Date: 2011-08-02 Completed Date: 2011-09-30 Revised Date: 2011-09-30 |
Medline Journal Info:
|
Nlm Unique ID: 0075674 Medline TA: Clin Orthop Relat Res Country: United States |
Other Details:
|
Languages: eng Pagination: 2590-7 Citation Subset: AIM; IM |
Affiliation:
|
Department of Orthopaedic Surgery, Imperial College, Charing Cross Hospital Campus, London SW7 2AZ, UK. a.hart@imperial.ac.uk |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acetabulum
/
physiopathology,
radiography,
surgery* Adult Aged Analysis of Variance Arthroplasty, Replacement, Hip / adverse effects, instrumentation* Chromium / blood Cobalt / blood* Female Hip Joint / physiopathology, radiography, surgery* Hip Prosthesis* Humans Linear Models London Male Middle Aged Prospective Studies Prosthesis Design Risk Assessment Risk Factors Sex Factors Surface Properties Time Factors Tomography, X-Ray Computed |
| Chemical | |
Reg. No./Substance:
|
7440-47-3/Chromium; 7440-48-4/Cobalt |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Surfactant-stabilized emulsion increases gentamicin elution from bone cement.
Next Document: Laparoscopic removal of intravesical mesh following pelvic organ prolapse mesh surgery.