Document Detail

Instrumental control of cardioacceleration induced by central electrical stimulation.
MedLine Citation:
PMID:  7280696     Owner:  NLM     Status:  MEDLINE    
Each of four monkeys (Macaca mulatta) was operantly conditioned to slow and to speed heart rate through a shock-avoidance procedure. During these sessions, electrical brain stimulation that produced tachycardia and pressor responses was delivered on alternate, 64-second segments to one of several brain regions. All animals were able to attenuate the increases in heart rate produced by brain stimulation during the slowing sessions when posterior hypothalamic and striatal regions were stimulated but not when anterior hypothalamic or subthalamic areas were stimulated. During speeding or control sessions during which heart rate was monitored, brain stimulation continued to increase heart rate.
J A Joseph; B T Engel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Science (New York, N.Y.)     Volume:  214     ISSN:  0036-8075     ISO Abbreviation:  Science     Publication Date:  1981 Oct 
Date Detail:
Created Date:  1981-11-22     Completed Date:  1981-11-22     Revised Date:  2007-03-19    
Medline Journal Info:
Nlm Unique ID:  0404511     Medline TA:  Science     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  341-3     Citation Subset:  IM    
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MeSH Terms
Avoidance Learning
Blood Pressure
Brain / physiology*
Corpus Striatum / physiology
Electric Stimulation
Heart Rate*
Hypothalamus / physiology
Macaca mulatta
Thalamic Nuclei / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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