Document Detail

Institutional review board (IRB) and ethical issues in clinical research.
MedLine Citation:
PMID:  22323947     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Clinical research has expanded tremendously in the past few decades and consequently there has been growing interest in the ethical guidelines that are being followed for the protection of human subjects. This review summarizes historical scandals and social responses chronologically from World War II to the Death of Ellen Roche (2001) to emphasize the lessons we must learn from history. International ethical guidelines for studies with human subjects are also briefly described in order to understand the circumstances of clinical research. The tasks and responsibilities of the institutions and investigators in human subject research to preserve the safety and welfare of research subjects are summarized. Next, several debated ethical issues and insights are arranged as controversial topics. This brief review and summary seeks to highlight important arguments and make suggestions to institutional review boards (IRBs) to contribute to the future evolution of ethics in clinical research as we advance forward.
Won Oak Kim
Related Documents :
22427717 - Technology commercialization effects on the conduct of research in higher education.
22907687 - Directions in implementation research methods for behavioral and social science.
22495407 - Directions for advancing the study of work transitions in the 21st century.
22904477 - Ps2-09: the hmo research network: growth, governance and administrative gaps.
17570887 - Get the news on physical activity research: a content analysis of physical activity res...
16172747 - A conceptual and practical overview of cdna microarray technology: implications for bas...
Publication Detail:
Type:  Journal Article     Date:  2012-01-25
Journal Detail:
Title:  Korean journal of anesthesiology     Volume:  62     ISSN:  2005-7563     ISO Abbreviation:  Korean J Anesthesiol     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-02-10     Completed Date:  2012-10-02     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101502451     Medline TA:  Korean J Anesthesiol     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  3-12     Citation Subset:  -    
Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Modified trans-middle temporal gyrus approach for trigonal tumor to preserve visual field.
Next Document:  Bispectral index and their relation with consciousness of the patients who receive desflurane or sev...