| Inspiratory muscle training in patients with heart failure and inspiratory muscle weakness: a randomized trial. | |
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MedLine Citation:
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PMID: 16487841 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: This study sought to evaluate the effects of inspiratory muscle training in inspiratory muscle strength, as well as in functional capacity, ventilatory responses to exercise, recovery oxygen uptake kinetics, and quality of life in patients with chronic heart failure (CHF) and inspiratory muscle weakness. BACKGROUND: Patients with CHF may have reduced strength and endurance in inspiratory muscles, which may contribute to exercise intolerance and is associated with a poor prognosis. METHODS: Thirty-two patients with CHF and weakness of inspiratory muscles (maximal inspiratory pressure [Pi(max)] <70% of predicted) were randomly assigned to a 12-week program of inspiratory muscle training (IMT, 16 patients) or to a placebo-inspiratory muscle training (P-IMT, 16 patients). The following measures were obtained before and after the program: Pi(max) at rest and 10 min after maximal exercise; peak oxygen uptake, circulatory power, ventilatory oscillations, and oxygen kinetics during early recovery (VO2/t-slope); 6-min walk test; and quality of life scores. RESULTS: The IMT resulted in a 115% increment Pi(max), 17% increase in peak oxygen uptake, and 19% increase in the 6-min walk distance. Likewise, circulatory power increased and ventilatory oscillations were reduced. The VO2/t-slope was improved during the recovery period, and quality of life scores improved. CONCLUSIONS: In patients with CHF and inspiratory muscle weakness, IMT results in marked improvement in inspiratory muscle strength, as well as improvement in functional capacity, ventilatory response to exercise, recovery oxygen uptake kinetics, and quality of life. |
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Authors:
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Pedro Dall'Ago; Gaspar R S Chiappa; Henrique Guths; Ricardo Stein; Jorge P Ribeiro |
Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't Date: 2006-01-26 |
Journal Detail:
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Title: Journal of the American College of Cardiology Volume: 47 ISSN: 1558-3597 ISO Abbreviation: J. Am. Coll. Cardiol. Publication Date: 2006 Feb |
Date Detail:
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Created Date: 2006-02-20 Completed Date: 2006-04-28 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8301365 Medline TA: J Am Coll Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 757-63 Citation Subset: AIM; IM |
Affiliation:
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Department of Physiological Sciences, Fundação Faculdade Federal de Ciências Médicas de Porto Alegre, Porto Alegre, Brazil. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Breathing Exercises* Exercise Test Exercise Tolerance Female Heart Failure / complications*, physiopathology Humans Inhalation* Inspiratory Capacity Male Middle Aged Muscle Weakness / etiology, physiopathology, rehabilitation* Oxygen Consumption Quality of Life Respiratory Muscles / physiopathology* Walking |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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