Document Detail

Inspiratory muscle training improves oxygen uptake efficiency slope in patients with chronic heart failure.
MedLine Citation:
PMID:  19809347     Owner:  NLM     Status:  MEDLINE    
PURPOSE: Inspiratory muscle training (IMT) improves exercise capacity and ventilatory responses to exercise in patients with chronic heart failure (CHF) with inspiratory muscle weakness (IMW). We analyzed the effects of IMT on the oxygen uptake efficiency slope (OUES) in this patient population.
METHODS: Thirty-two CHF patients with IMW (maximal inspiratory pressure [PImax] < 70% of predicted) were randomly assigned to either a 12-week program of IMT (IMT, n = 16) or placebo-IMT (P-IMT, n = 16). PImax and OUES were obtained before and after the intervention.
RESULTS: Inspiratory muscle training resulted in 115% increment in PImax (5.9 +/- 0.9 vs 12.7 +/- 0.9 kPa; P < .001) and in significant improvement in OUES (1,554 +/- 617 to 2,037 +/- 747 mL min O2/L min of minute ventilation; P = .001). There were no significant changes in the P-IMT group. There was a significant association between the changes in PImax and OUES (r = 0.82, P < .01).
CONCLUSION: In CHF patients with IMW, IMT results in a significant increase in OUES.
Ricardo Stein; Gaspar R Chiappa; Henrique Güths; Pedro Dall'Ago; Jorge P Ribeiro
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of cardiopulmonary rehabilitation and prevention     Volume:  29     ISSN:  1932-751X     ISO Abbreviation:  J Cardiopulm Rehabil Prev     Publication Date:    2009 Nov-Dec
Date Detail:
Created Date:  2009-11-26     Completed Date:  2011-01-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101291247     Medline TA:  J Cardiopulm Rehabil Prev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  392-5     Citation Subset:  IM    
Exercise PathophysiologyResearch Laboratory, Hospital deClinicas de Porto Alegre, Rua RamiroBarcelos 2350, 90035-007 PortoAlegre, Rio Grande do Sul, Brazil.
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MeSH Terms
Chronic Disease
Exercise Test
Exercise Therapy
Exercise Tolerance*
Heart Failure / therapy*
Inspiratory Capacity
Linear Models
Oxygen Consumption*
Respiratory Muscles / physiology*
Statistics, Nonparametric

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