| Insight and resistance in patients with obsessive-compulsive disorder. | |
MedLine Citation:
|
PMID: 11244376 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The aim of this study was to evaluate the degree of insight and resistance in a sample of obsessive-compulsive patients, and the predictive value of poor insight with respect to response to treatment with serotonin reuptake inhibitors (SRIs). Ninety-three patients fulfilling DSM-IV criteria for obsessive-compulsive disorder were evaluated. Seventy patients were treated with an SRI in a 24-week open-label trial. Sixteen percent of the patients did not recognize obsessions and compulsions as unreasonable or senseless. Fifty-two percent of the patients did not try to resist, 72% had little or no control over obsessions, and 64% were not able to exercise an effective control over compulsions. Patients with poor insight had a greater severity of obsessive-compulsive symptoms, a higher rate of schizophrenia spectrum disorders in their first-degree relatives and a higher frequency of a history of psychiatric disorders during childhood. Fifty-two percent of the patients with normal insight responded to SRIs, whereas none of the patients with poor insight were found to be responders. These results suggest the utility of the assessment of insight and resistance in obsessive-compulsive patients, also for the prediction of response to treatment with SRIs. |
Authors:
|
F Catapano; R Sperandeo; F Perris; M Lanzaro; M Maj |
Related Documents
:
|
472076 - The leyton obsessional inventory: an analysis of the responses of 73 obsessional patients. 21216546 - In situ expression of cd23 in lymph nodes of patients with kimura's disease. 17004666 - Effects of comfort warming on preoperative patients. 7608996 - Learning from unsuccessful sex therapy patients. 20852436 - Normal tension glaucoma in patients with obstructive sleep apnea/hypopnea syndrome. 18187496 - Influence of atherosclerosis on the relationship between anaemia and mortality risk in ... |
Publication Detail:
|
Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
|
Title: Psychopathology Volume: 34 ISSN: 0254-4962 ISO Abbreviation: Psychopathology Publication Date: 2001 Mar-Apr |
Date Detail:
|
Created Date: 2001-03-13 Completed Date: 2001-06-21 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 8401537 Medline TA: Psychopathology Country: Switzerland |
Other Details:
|
Languages: eng Pagination: 62-8 Citation Subset: IM |
Copyright Information:
|
Copyright 2001 S. Karger AG, Basel |
Affiliation:
|
Department of Psychiatry, First Medical School, University of Naples, Italy. catapano@unina.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Drug Administration Schedule Drug Resistance Female Humans Male Middle Aged Obsessive-Compulsive Disorder / diagnosis*, drug therapy, psychology* Predictive Value of Tests Self Concept* Serotonin Uptake Inhibitors / administration & dosage, therapeutic use Severity of Illness Index Treatment Outcome |
| Chemical | |
Reg. No./Substance:
|
0/Serotonin Uptake Inhibitors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Depressive symptoms and academic self-image in adolescence.
Next Document: Evaluation of the multiaxial system of ICD-10 (preliminary praft): correlations between multiaxial a...