| Inotropic agents and infarct size. Theoretical and practical considerations. | |
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MedLine Citation:
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PMID: 1258787 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Recent data demonstrating the ability of interventions that alter the balance between myocardial oxygen demand and supply to affect infarct size are reviewed. The effects of inotropic agents on the determinants of myocardial oxygen consumption and coronary blood flow are discussed relative to the potential of these drugs to decrease or increase infarct size in the experimental animal and in man. The applicability of the animal data to the clinical situation is discussed and, on the basis of these considerations, guidelines are presented for the use of inotropic agents in patients with acute myocardial infarction. |
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Authors:
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M Lesch |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The American journal of cardiology Volume: 37 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 1976 Mar |
Date Detail:
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Created Date: 1976-06-02 Completed Date: 1976-06-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 508-13 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Animals Cardiac Volume / drug effects Digitalis Glycosides / pharmacology* Heart / physiopathology Heart Rate / drug effects Humans Isoproterenol / pharmacology* Myocardial Contraction / drug effects* Myocardial Infarction / complications, metabolism, pathology* Norepinephrine / pharmacology* Oxygen / blood Oxygen Consumption / drug effects Pressure |
| Chemical | |
Reg. No./Substance:
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0/Digitalis Glycosides; 51-41-2/Norepinephrine; 7683-59-2/Isoproterenol; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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