Document Detail


Inositol treatment of Alzheimer's disease: a double blind, cross-over placebo controlled trial.
MedLine Citation:
PMID:  8843494     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
1. A double-blind controlled crossover trial of 6 gm of inositol daily vs glucose for one month each was carried out in 11 Alzheimer patients. 2. Overall CAMCOG scores showed a trend for greater improvement with inositol that was not significant. 3. Language and orientation improved significantly more on inositol than on placebo. There were no serious side effects. 4. Higher doses of inositol should be studied in Alzheimer's Disease for longer periods.
Authors:
Y Barak; J Levine; A Glasman; A Elizur; R H Belmaker
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Progress in neuro-psychopharmacology & biological psychiatry     Volume:  20     ISSN:  0278-5846     ISO Abbreviation:  Prog. Neuropsychopharmacol. Biol. Psychiatry     Publication Date:  1996 May 
Date Detail:
Created Date:  1997-01-03     Completed Date:  1997-01-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8211617     Medline TA:  Prog Neuropsychopharmacol Biol Psychiatry     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  729-35     Citation Subset:  IM    
Affiliation:
Abarbanel Mental Health Center, Bat Yam, Israel.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Alzheimer Disease / drug therapy*,  psychology
Cross-Over Studies
Double-Blind Method
Female
Humans
Inositol / therapeutic use*
Language
Orientation / physiology
Psychiatric Status Rating Scales
Chemical
Reg. No./Substance:
6917-35-7/Inositol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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