| Innovative diagnostic technologies and their significance for personalized medicine. | |
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MedLine Citation:
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PMID: 20560675 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Molecular diagnostics plays an important role in the development of personalized medicine. Innovative diagnostic technologies that are increasingly utilized in personalizing treatment include novel polymerase chain reaction (PCR), direct molecular analysis without amplification, DNA sequencing, biochips/microarrays, and nanobiotechnologies. Technologies for detection of copy number variations, single nucleotide polymorphisms, and cytogenetic alterations provide basic information for personalized medicine. Molecular diagnostic technologies are used for the detection of biomarkers, which may form the common basis of diagnostics and therapeutics. Finally, integration of diagnostics with therapeutics is an important component of personalized medicine. |
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Authors:
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Kewal K Jain |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Molecular diagnosis & therapy Volume: 14 ISSN: 1177-1062 ISO Abbreviation: Mol Diagn Ther Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-06-21 Completed Date: 2011-01-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101264260 Medline TA: Mol Diagn Ther Country: New Zealand |
Other Details:
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Languages: eng Pagination: 141-7 Citation Subset: IM |
Affiliation:
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Jain PharmaBiotech, Basel, Switzerland. jain@pharmabiotech.ch |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Biological Markers
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analysis Cytogenetics Genetic Variation Humans Individualized Medicine / methods* Molecular Diagnostic Techniques / methods* Nanotechnology Oligonucleotide Array Sequence Analysis |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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