Document Detail


Innovation - drugs and diagnostics.
MedLine Citation:
PMID:  17656390     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The control of antibiotic resistance presents a complex and multifaceted challenge. Professional societies, governments and international agencies, including the WHO, have identified a strategy that emphasizes the importance of microbiological surveillance, monitoring antibiotic use, prudent prescribing, education of healthcare professionals and the public and encouraging the development of new drugs and other technologies. The flow of new classes of antibiotic has substantially declined at a time when resistance rates and new problems have increased significantly. The decline in prescribing rates, the emphasis on the use of generics, the multiple hurdles to be negotiated with licensing authorities and reimbursement agencies are in part responsible. In addition, the failure of genomic-based drug development to show a return on investment has compounded this problem. With this background, a number of organizations have made efforts to raise these concerns with governments, academia, funding agencies and other relevant parties. The Specialist Advisory Committee on Antimicrobial Resistance recognized the need to address the technology gap. A European Union Intergovernmental Conference was organized on behalf of the UK Department of Health entitled 'Antibiotic resistance - action to promote new technologies' in December 2005. The conference gathered together delegates from academia, industry, funding agencies, healthcare management, the European Medicines Evaluation Agency, The European Centre for Disease Prevention and Control, European Directorates and representatives of Member States. Its recommendations have been published.
Authors:
Roger Finch
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of antimicrobial chemotherapy     Volume:  60 Suppl 1     ISSN:  0305-7453     ISO Abbreviation:  J. Antimicrob. Chemother.     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-07-27     Completed Date:  2007-10-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7513617     Medline TA:  J Antimicrob Chemother     Country:  England    
Other Details:
Languages:  eng     Pagination:  i79-82     Citation Subset:  IM    
Affiliation:
Division of Microbiology and Infectious Diseases, Molecular Medical Sciences, Clinical Sciences Building, University of Nottingham and Nottingham University Hospitals NHS Trust, City Hospital Campus, Nottingham NG5 1PB, UK. r.finch@nottingham.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Anti-Bacterial Agents / pharmacology*,  therapeutic use*
Bacterial Infections / diagnosis*,  drug therapy*
Drug Utilization / trends*
Humans
Research*
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents

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