Document Detail

Innovar treatment for Meniere's disease.
MedLine Citation:
PMID:  10320074     Owner:  NLM     Status:  MEDLINE    
Patients with intractable vertigo due to clinical Meniere's disease were offered treatment with Innovar, a neurolept analgesic. The patients were from a single clinical practice, had failed conventional dietary and medical treatment and were eligible on clinical grounds for endolymphatic sac surgery. After a follow-up of 2-8 years, 58% of patients had long-lasting relief of vertigo. Hearing was not affected. Risk factors for a favorable response were male gender, fluctuating hearing, and early stage of the disorder. Innovar is a safe, cost-effective second-line therapy for patients with Meniere's disease who have failed conventional first-line medical therapy.
G A Gates
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta oto-laryngologica     Volume:  119     ISSN:  0001-6489     ISO Abbreviation:  Acta Otolaryngol.     Publication Date:  1999 Mar 
Date Detail:
Created Date:  1999-06-30     Completed Date:  1999-06-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370354     Medline TA:  Acta Otolaryngol     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  189-93     Citation Subset:  IM    
Department of Otolaryngology--Head and Neck Surgery, University of Washington School of Medicine, Seattle, USA.
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MeSH Terms
Analgesics / therapeutic use*
Droperidol / therapeutic use*
Fentanyl / therapeutic use*
Follow-Up Studies
Meniere Disease / drug therapy*
Middle Aged
Risk Factors
Time Factors
Treatment Outcome
Reg. No./Substance:
0/Analgesics; 437-38-7/Fentanyl; 548-73-2/Droperidol; 8067-59-2/Innovar

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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