Document Detail

Innate lymphoid cells--how did we miss them?
MedLine Citation:
PMID:  23292121     Owner:  NLM     Status:  MEDLINE    
Innate lymphoid cells (ILCs) are newly identified members of the lymphoid lineage that have emerging roles in mediating immune responses and in regulating tissue homeostasis and inflammation. Here, we review the developmental relationships between the various ILC lineages that have been identified to date and summarize their functions in protective immunity to infection and their pathological roles in allergic and autoimmune diseases.
Jennifer A Walker; Jillian L Barlow; Andrew N J McKenzie
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2013-01-07
Journal Detail:
Title:  Nature reviews. Immunology     Volume:  13     ISSN:  1474-1741     ISO Abbreviation:  Nat. Rev. Immunol.     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-25     Completed Date:  2013-03-21     Revised Date:  2014-02-20    
Medline Journal Info:
Nlm Unique ID:  101124169     Medline TA:  Nat Rev Immunol     Country:  England    
Other Details:
Languages:  eng     Pagination:  75-87     Citation Subset:  IM    
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MeSH Terms
Asthma / genetics,  immunology
Biological Evolution
Cell Communication / immunology
Cell Lineage / genetics,  immunology
Host-Pathogen Interactions / genetics,  immunology
Hypersensitivity / genetics,  immunology
Immunity, Innate / genetics,  immunology*
Inflammatory Bowel Diseases / genetics,  immunology
Lymphocyte Subsets / immunology,  metabolism
Lymphocytes / immunology*,  metabolism
Grant Support
MC_U105178805//Medical Research Council

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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