Document Detail


Innate immunity in respiratory syncytial virus bronchiolitis.
MedLine Citation:
PMID:  18075829     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Respiratory syncytial virus (RSV) bronchiolitis is a serious and distressing illness, which occurs almost exclusively in infants under one year of age. Although the majority of all children will have experienced an infection with RSV by the time they reach their second birthday, only a minority develop bronchiolitis. It is unclear why some otherwise healthy infants develop this severe illness and many studies have investigated whether or not this relates to an over-exuberant immunological response to the infection. It is increasingly being recognized that the innate immune response may play a key role.
Authors:
Rosalind L Smyth
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Experimental lung research     Volume:  33     ISSN:  0190-2148     ISO Abbreviation:  Exp. Lung Res.     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-12-13     Completed Date:  2008-02-28     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8004944     Medline TA:  Exp Lung Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  543-7     Citation Subset:  IM    
Affiliation:
Division of Child Health, School of Reproductive and Developmental Medicine, University of Liverpool, Alder Hey Children's Hospital, Liverpool, UK. r.l.smyth@liv.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Bronchi / virology
Bronchiolitis, Viral / immunology*,  virology
Humans
Immunity, Innate / immunology*
Respiratory Syncytial Virus Infections / complications,  immunology*
Respiratory Syncytial Viruses / pathogenicity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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