| Injury of the spino-thalamo-cortical pathway is necessary for central post-stroke pain. | |
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MedLine Citation:
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PMID: 20699616 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: We investigated the relationship between injury of the spino-thalamo-cortical pathway (STP) and central post-stroke pain (CPSP) in patients with intracerebral hemorrhage, using diffusion tensor tractography (DTT). METHODS: 30 consecutive chronic patients, in whom integrity of the STP and the medial lemnisco-thalamo-cortical pathway (MLP) were spared in both hemispheres, were recruited. We classified the patients into two groups according to the presence of the CPSP. DTTs were obtained using the FMRIB Software Library. Fractional anisotropy (FA), mean diffusivity (MD), and tract volume were measured. A laterality index (LI) was used to determine asymmetry of DTT parameters between the hemispheres. RESULTS: The LI for tract volume of the STP in the CPSP group was lower than that of the non-CPSP group (p = 0.000). However, there were no differences between the CPSP group and non-CPSP group for the LIs of FA or MD of the STP or for the LIs of FA, MD, or tract volume of the MLP (p > 0.05). CONCLUSIONS: Decrease of tract volume without changes in the STP FA or MD values in the CPSP group indicates partial injury of STP. Therefore, injury of the STP seems to be a requirement for the development of CPSP in patients with intracerebral hemorrhage. |
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Authors:
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Ji Heon Hong; Dai Seg Bai; Jin Young Jeong; Byung Yun Choi; Chul Hoon Chang; Seong Ho Kim; Sang Ho Ahn; Sung Ho Jang |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-08-10 |
Journal Detail:
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Title: European neurology Volume: 64 ISSN: 1421-9913 ISO Abbreviation: Eur. Neurol. Publication Date: 2010 |
Date Detail:
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Created Date: 2010-09-03 Completed Date: 2010-12-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0150760 Medline TA: Eur Neurol Country: Switzerland |
Other Details:
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Languages: eng Pagination: 163-8 Citation Subset: IM |
Copyright Information:
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Copyright (c) 2010 S. Karger AG, Basel. |
Affiliation:
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Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Taegu, Republic of Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Anisotropy Brain Mapping Cerebral Cortex / injuries, physiopathology* Diffusion Magnetic Resonance Imaging / methods Female Humans Male Middle Aged Neural Pathways / injuries, physiopathology Pain / etiology, pathology* Pain Measurement Spinal Cord / physiopathology* Stroke / complications Thalamus / injuries, physiopathology* |
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