Document Detail


Injury of the spino-thalamo-cortical pathway is necessary for central post-stroke pain.
MedLine Citation:
PMID:  20699616     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: We investigated the relationship between injury of the spino-thalamo-cortical pathway (STP) and central post-stroke pain (CPSP) in patients with intracerebral hemorrhage, using diffusion tensor tractography (DTT).
METHODS: 30 consecutive chronic patients, in whom integrity of the STP and the medial lemnisco-thalamo-cortical pathway (MLP) were spared in both hemispheres, were recruited. We classified the patients into two groups according to the presence of the CPSP. DTTs were obtained using the FMRIB Software Library. Fractional anisotropy (FA), mean diffusivity (MD), and tract volume were measured. A laterality index (LI) was used to determine asymmetry of DTT parameters between the hemispheres.
RESULTS: The LI for tract volume of the STP in the CPSP group was lower than that of the non-CPSP group (p = 0.000). However, there were no differences between the CPSP group and non-CPSP group for the LIs of FA or MD of the STP or for the LIs of FA, MD, or tract volume of the MLP (p > 0.05).
CONCLUSIONS: Decrease of tract volume without changes in the STP FA or MD values in the CPSP group indicates partial injury of STP. Therefore, injury of the STP seems to be a requirement for the development of CPSP in patients with intracerebral hemorrhage.
Authors:
Ji Heon Hong; Dai Seg Bai; Jin Young Jeong; Byung Yun Choi; Chul Hoon Chang; Seong Ho Kim; Sang Ho Ahn; Sung Ho Jang
Related Documents :
14726546 - Long-term outcome of acute spinal cord ischemia syndrome.
11136156 - Functional decline in independent elders after minor traumatic injury.
24595926 - Tubeless percutaneous nephrolithotomy: spinal versus general anesthesia.
23861866 - Quantification of collagen ultrastructure after penetrating keratoplasty - implications...
2342006 - Prospective comparative study of cefotetan with piperacillin for prophylaxis against in...
20358306 - Alcohol absorption modification after a laparoscopic sleeve gastrectomy due to obesity.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-08-10
Journal Detail:
Title:  European neurology     Volume:  64     ISSN:  1421-9913     ISO Abbreviation:  Eur. Neurol.     Publication Date:  2010  
Date Detail:
Created Date:  2010-09-03     Completed Date:  2010-12-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0150760     Medline TA:  Eur Neurol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  163-8     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2010 S. Karger AG, Basel.
Affiliation:
Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Taegu, Republic of Korea.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Anisotropy
Brain Mapping
Cerebral Cortex / injuries,  physiopathology*
Diffusion Magnetic Resonance Imaging / methods
Female
Humans
Male
Middle Aged
Neural Pathways / injuries,  physiopathology
Pain / etiology,  pathology*
Pain Measurement
Spinal Cord / physiopathology*
Stroke / complications
Thalamus / injuries,  physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Effects of various fluoride solutions on enamel erosion in vitro.
Next Document:  Tacrolimus-associated posterior reversible encephalopathy syndrome after solid organ transplantation...