Document Detail

Injection versus medialization laryngoplasty for the treatment of unilateral vocal fold paralysis: follow-up at six months.
MedLine Citation:
PMID:  20641088     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES/HYPOTHESIS: To determine whether injection laryngoplasty or medialization laryngoplasty is more effective in the long-term treatment of unilateral vocal fold paralysis (UVFP). STUDY DESIGN: A retrospective study of patients with UFVP who underwent either injection or medialization laryngoplasty at the University of Arkansas for Medical Sciences between July 29, 2003 and November 18, 2005. METHODS: The data analyzed included patient characteristics and type of intervention, along with the pretreatment and post-treatment parameters of videostrobolaryngoscopy, perceptual voice analysis, and patients' subjective assessment of voice handicap. RESULTS: Thirty-four patients were evaluated, 15 new and 19 from a previous study. The average time from intervention to post-treatment evaluation in the new cohort was 4.8 months (range, 1.5-10.5 months). The average time from intervention to post-treatment in the combined cohort was 6.4 months (range, 1-24 months). Improvements were demonstrated in each of the measured voice parameters in both the injection and the medialization groups, and no significant differences were found in the degree of improvement between the two groups. Limited data on aerodynamic and acoustic voice measurements showed a trend toward improvement in each treatment group. CONCLUSIONS: Injection and medialization laryngoplasty were comparable in achieving voice improvement at the average long-term follow-up of 6 months.
Kimberly N Vinson; Richard I Zraick; Felicia J Ragland
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Laryngoscope     Volume:  120     ISSN:  1531-4995     ISO Abbreviation:  Laryngoscope     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-30     Completed Date:  2010-09-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8607378     Medline TA:  Laryngoscope     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1802-7     Citation Subset:  IM    
Department of Otolaryngology, Vanderbilt Voice Center, Nashville, Tennessee, USA.
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MeSH Terms
Aged, 80 and over
Biocompatible Materials*
Cohort Studies
Collagen / administration & dosage*
Durapatite / administration & dosage*
Follow-Up Studies
Laryngoscopy / methods*
Middle Aged
Patient Satisfaction
Retrospective Studies
Video Recording
Vocal Cord Paralysis / surgery*
Vocal Cords / surgery*
Voice Quality
Reg. No./Substance:
0/Biocompatible Materials; 0/Cymetra; 1306-06-5/Durapatite; 9007-34-5/Collagen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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