| Injection of synthetic human growth hormone-releasing factors in dairy cows. 1. Effect on feed intake and milk yield and composition. | |
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MedLine Citation:
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PMID: 2896206 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Eighteen multiparous Holstein cows in the second half of their lactation were used to determine the effect of human growth hormone-releasing factor (1-44)NH2 and a fragment of growth hormone-releasing factor (1-29)NH2 on lactational performance and feed intake. Saline, the 44-amino acid peptide or the 29-amino acid fragment, at the same dose per injection (.2 nmol.kg-1) was injected intravenously at 4-h intervals for 10 d. Average milk yield, milk composition, feed intake, and feed efficiency were compared for the second half of each 10-d preinjection, injection, and post-injection period. Injections of the 44-amino acid peptide and the 29-amino acid fragment increased milk yield 18.6 and 14.6%, respectively. Feed intake was not changed, but feed efficiency was increased 23.9 and 18.8% over control following 44-amino acid peptide and the 29-amino acid fragment injection, respectively. The lactational response was not different between the two peptides for any of the variables measured. This study demonstrates the feasibility of using a growth hormone-releasing factor fragment as an alternative method of elevating milk yield in cattle via somatotropins. |
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Authors:
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G Pelletier; D Petitclerc; H Lapierre; M Bernier-Cardou; J Morisset; P Gaudreau; Y Couture; P Brazeau |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of dairy science Volume: 70 ISSN: 0022-0302 ISO Abbreviation: J. Dairy Sci. Publication Date: 1987 Dec |
Date Detail:
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Created Date: 1988-06-02 Completed Date: 1988-06-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 2985126R Medline TA: J Dairy Sci Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 2511-7 Citation Subset: IM |
Affiliation:
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Agriculture Canada Research Station, Lennoxville, Québec. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cattle / physiology* Eating / drug effects* Female Growth Hormone-Releasing Hormone / administration & dosage, analogs & derivatives*, pharmacology Injections, Intravenous Lactation / drug effects* Milk / analysis* Peptide Fragments / administration & dosage, pharmacology* Pregnancy Sermorelin |
| Chemical | |
Reg. No./Substance:
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0/Peptide Fragments; 0/somatotropin releasing hormone (1-44)amide; 86168-78-7/Sermorelin; 9034-39-3/Growth Hormone-Releasing Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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