| Injection of orexin A into the diagonal band of Broca induces sympathetic and hyperthermic reactions. | |
| | |
MedLine Citation:
|
PMID: 15276887 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
This experiment tested the effect of an injection of orexin A into the diagonal band of Broca on the sympathetic activity and body temperature. Concentration of glycerol into white fat of lumbar region, firing rates of sympathetic nerves to interscapular brown adipose tissue (IBAT), IBAT and colonic temperatures, and heart rate were monitored in urethane-anesthetized male Sprague-Dawley rats for 30 min before and 150 min after injections of orexin A (0.4 and 0.7 nmol) into the diagonal band of Broca. The same variables were monitored in control rats with an injection of saline. The results show that orexin A increases glycerol concentration, sympathetic firing rate, IBAT and colonic temperatures, and heart rate. The saline injection did not induce any modification. These findings suggest that the diagonal band of Broca is a cerebral structure involved in the induction of the hyperthermia due to orexin A. |
| | |
Authors:
|
M Monda; An Viggiano; Al Viggiano; F Fuccio; V De Luca |
Related Documents
:
|
3436857 - Differential effects of hypoxia on sleep of warm- and cold-acclimated rats. 15323767 - Measurement of the hall dynamo effect during magnetic reconnection in a high-temperatur... 12735627 - The effect of an endogenous na+, k+-atpase inhibitor on rat lens transparency and ultra... 834467 - Antagonism of cadmium and alloxan-induced hyperglycemia in rats by trigonella foenum gr... 7689357 - Atrial natriuretic peptide and bradykinin interaction on norepinephrine uptake in rat a... 1886417 - A reliable technique for chronic carotid arterial catheterization in the rat. |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Brain research Volume: 1018 ISSN: 0006-8993 ISO Abbreviation: Brain Res. Publication Date: 2004 Aug |
Date Detail:
|
Created Date: 2004-07-27 Completed Date: 2004-10-29 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0045503 Medline TA: Brain Res Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 265-71 Citation Subset: IM |
Affiliation:
|
Department of Experimental Medicine, Section of Human Physiology, Second University of Naples, via Costantinopoli 16, 80138 Naples, Italy. marcellino.monda@unina2.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Action Potentials
/
physiology Adipose Tissue / innervation, physiology* Analysis of Variance Animals Carrier Proteins / administration & dosage, physiology* Diagonal Band of Broca / physiology* Dose-Response Relationship, Drug Fever / chemically induced Glycerol / metabolism Intracellular Signaling Peptides and Proteins* Male Microinjections Neuropeptides / administration & dosage, physiology* Rats Rats, Sprague-Dawley Sympathetic Nervous System / physiology* Thermogenesis / physiology* |
| Chemical | |
Reg. No./Substance:
|
0/Carrier Proteins; 0/Intracellular Signaling Peptides and Proteins; 0/Neuropeptides; 0/orexins; 56-81-5/Glycerol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effect of lambda-carrageenan-induced inflammatory pain on brain uptake of codeine and antinociceptio...
Next Document: Antinociceptive effects of bethanechol or dimethylphenylpiperazinium in models of phasic or incision...