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Injection of gadolinium contrast through pediatric central venous catheters: a safety study.
MedLine Citation:
PMID:  22526282     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Catheter rupture during CT angiography has prompted policies prohibiting the use of electronic injectors with peripherally inserted central venous catheters (PICCs) not only for CT but also for MRI. Consequently, many institutions mandate hand injection for MR angiography, limiting precision of infusion rates and durations of delivery. OBJECTIVE: To determine whether electronic injection of gadolinium-based contrast media through a range of small-caliber, single-lumen PICCs would be safe without risk of catheter rupture over the range of clinical protocols and determine whether programmed flow rates and volumes were realized when using PICCs for contrast delivery. MATERIALS AND METHODS: Experiments were performed and recorded using the Medrad Spectris Solaris EP MR Injection System. PICC sizes, contrast media and flow rates were based on common institutional protocols. RESULTS: No catheters were damaged during any experiments. Mean difference between programmed and delivered volume was 0.07 ± 0.10 mL for all experiments. Reduced flow rates and prolonged injection durations were observed when the injector's pressure-limiting algorithm was triggered, only in protocols outside the clinical range. CONCLUSION: PICCs commonly used in children can withstand in vitro power injection of gadolinium-based contrast media at protocols significantly above clinical levels.
Authors:
John M Moriarty; Geoffrey L Kung; Yanerys Ramos; Abbas N Moghaddam; Daniel B Ennis; J Paul Finn
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-4-24
Journal Detail:
Title:  Pediatric radiology     Volume:  -     ISSN:  1432-1998     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-4-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0365332     Medline TA:  Pediatr Radiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Radiological Sciences, David Geffen School of Medicine, University of California, 10945 Le Conte Ave., Ueberroth Bldg, Ste. 3371, Los Angeles, CA, 90095-7206, USA, jmoriarty@mednet.ucla.edu.
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