Document Detail


Injection of (99m)Tc-labeled sulfur colloid the day before operation for breast cancer sentinel lymph node mapping is as successful as injection the day of operation.
MedLine Citation:
PMID:  15619484     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: We investigated whether the timing of injection of (99m)Tc-labeled sulfur colloid (radiocolloid) significantly influenced the success of breast cancer sentinel lymph node (SLN) mapping. METHODS: Review of a prospective SLN database. Five hundred forty-six consecutive breast SLN mapping patients were analyzed. A dual radiocolloid/blue dye technique was used in all patients. RESULTS: The SLN identification rate was similar among those patients injected the day prior (100%) and those injected the day of operation (99%, P = 0.14). A "hot" SLN was identified in 99% of patients injected the day prior and in 97% (P = 0.17) injected the day of operation. The mean number of SLNs was greater among those injected the day prior (2.71) than among those injected the day of operation (2.33, P = 0.01). There were no differences in the rates of SLN metastases. CONCLUSIONS: Radiocolloid injection the day before operation is an acceptable and logistically advantageous technique for breast cancer SLN mapping.
Authors:
Richard J Gray; Barbara A Pockaj; Michael C Roarke
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American journal of surgery     Volume:  188     ISSN:  0002-9610     ISO Abbreviation:  Am. J. Surg.     Publication Date:  2004 Dec 
Date Detail:
Created Date:  2004-12-27     Completed Date:  2005-02-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370473     Medline TA:  Am J Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  685-9     Citation Subset:  AIM; IM    
Affiliation:
Department of Surgery, Section of Surgical Oncology, CB Surgery, Mayo Clinic, Scottsdale, AZ 85259, USA. gray.richard@mayo.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Breast Neoplasms / pathology,  radionuclide imaging*,  surgery*
Cohort Studies
Female
Humans
Injections, Intravenous
Lymph Nodes / pathology,  radionuclide imaging
Mastectomy / methods
Middle Aged
Neoplasm Invasiveness / pathology,  radionuclide imaging*
Neoplasm Staging
Preoperative Care / methods
Probability
Prospective Studies
Risk Assessment
Sensitivity and Specificity
Sentinel Lymph Node Biopsy / methods*
Technetium Tc 99m Sulfur Colloid / diagnostic use*
Time Factors
Chemical
Reg. No./Substance:
0/Technetium Tc 99m Sulfur Colloid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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