Document Detail

Injectable fillers: an American perspective.
MedLine Citation:
PMID:  19528908     Owner:  NLM     Status:  MEDLINE    
Since 1981, there has been a significant repertoire of United States Food and Drug Administrtion (FDA) approved fillers for both cosmetic rejuvenation and facial lipoatrophy. Currently available dermal fillers include bovine, human and porcine collagens, hyaluronic acids of animal and biosynthetic origin, poly-L-lactic acid, calcium hydroxylapatite, and polymethylmethacrylate. Many of these fillers were first available in Europe and Canada before their arrival in the United States (USA) and many of the complications known about these products have come from studies conducted both in the USA and abroad. Several of the fillers that are currently available abroad or are used in the USA off-label have been associated with significant complications. The authors review three of these fillers: liquid injectable silicone, DermaLive/DermaDeep, and Bio-Alcamid.
N M Curcio; L C Parish
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Giornale italiano di dermatologia e venereologia : organo ufficiale, Società italiana di dermatologia e sifilografia     Volume:  144     ISSN:  0392-0488     ISO Abbreviation:  G Ital Dermatol Venereol     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-06-16     Completed Date:  2009-11-13     Revised Date:  2012-07-30    
Medline Journal Info:
Nlm Unique ID:  8102852     Medline TA:  G Ital Dermatol Venereol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  271-9     Citation Subset:  IM    
Division of Dermatology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
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MeSH Terms
Acrylic Resins / administration & dosage,  adverse effects
Biocompatible Materials / administration & dosage*,  adverse effects,  classification
Collagen / administration & dosage
Cosmetic Techniques*
Dermatologic Agents / administration & dosage*,  adverse effects,  classification
Durapatite / administration & dosage
Granuloma, Foreign-Body / etiology
Hyaluronic Acid / administration & dosage
Injections, Intradermal
Injections, Subcutaneous
Lactic Acid / administration & dosage
Polymers / administration & dosage
Polymethyl Methacrylate / administration & dosage
Silicone Gels / administration & dosage,  adverse effects
Skin Aging / drug effects*
United States
United States Food and Drug Administration
Reg. No./Substance:
0/Acrylic Resins; 0/Bio-Alcamid; 0/Biocompatible Materials; 0/Dermatologic Agents; 0/Polymers; 0/Silicone Gels; 1306-06-5/Durapatite; 26100-51-6/poly(lactic acid); 50-21-5/Lactic Acid; 9004-61-9/Hyaluronic Acid; 9007-34-5/Collagen; 9011-14-7/Polymethyl Methacrylate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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