| Initiation and inhibition of shivering in the rat: interaction between peripheral and central factors. | |
| | |
MedLine Citation:
|
PMID: 7094436 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
1. Unanaesthetized, female white laboratory rats were subjected to almost square-wave changes in ambient temperature, from 20 degrees C to 35 degrees C, in a small climatic chamber. 2. Intracerebroventricular injections of serotonin and methysergide were made in shivering, unanaesthetized rats. 3. The integrated electromyogram of m. suprascapularis was recorded as a quantitative measure of shivering activity to monitor the effects of the above procedures. 4. Both warm transients and serotonin inhibited shivering, but methysergide blocked only the effect of serotonin. |
| | |
Authors:
|
N J Dawson; J L Malcolm |
Related Documents
:
|
5647836 - Showering as a coolant for rats exposed to heat. 2578366 - Effects of body temperature elevation on auditory nerve-brain-stem evoked responses and... 2793726 - Blunted febrile response to intravenous endotoxin in starved rats. 7752956 - Effects of age, reproductive status and ambient temperature on skin temperature regulat... 15756926 - Repeated restraint stress reduces opioid receptor binding in different rat cns structures. 5275866 - A method of stimulating different segments of the autonomic outflow from the spinal col... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Clinical and experimental pharmacology & physiology Volume: 9 ISSN: 0305-1870 ISO Abbreviation: Clin. Exp. Pharmacol. Physiol. Publication Date: 1982 Jan-Feb |
Date Detail:
|
Created Date: 1982-09-24 Completed Date: 1982-09-24 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0425076 Medline TA: Clin Exp Pharmacol Physiol Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 89-93 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Central Nervous System / physiology* Electromyography Female Injections, Intraventricular Methysergide / pharmacology Peripheral Nerves / physiology* Rats Serotonin / pharmacology Shivering / drug effects* Time Factors |
| Chemical | |
Reg. No./Substance:
|
361-37-5/Methysergide; 50-67-9/Serotonin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The effect of chlorpromazine pretreatment on the narcotic antagonistic potency of naloxone in mice.
Next Document: The effect of oral aluminium therapy on plasma aluminium levels in patients with chronic renal failu...