| Initiation of antiretroviral therapy in the hospitalized patient with an acute AIDS-related opportunistic infection and other conditions: no time to lose. | |
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MedLine Citation:
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PMID: 19358776 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Treatment guidelines have recently become more definitive regarding the optimal timing for initiation of combination antiretroviral therapy (ART) in the setting of an acute AIDS-related opportunistic infection (OI). These recent changes reflect new data from a prospective, randomized study and several retrospective studies, all of which support earlier initiation of ART during an OI. These studies focus on OIs for which effective antimicrobial therapy exists. For AIDS-related conditions that lack effective antimicrobial therapy, there are few studies to help inform the optimal timing to initiate ART, but most clinicians initiate ART early, as little else can be offered to these patients. For patients with HIV admitted for non-AIDS-related conditions, there are few data that directly address the optimal timing for ART. Initiating ART in the hospitalized patient can be challenging and requires a well-coordinated multidisciplinary team with expertise in ART management. |
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Authors:
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Philip Grant; Andrew Zolopa |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Current HIV/AIDS reports Volume: 6 ISSN: 1548-3576 ISO Abbreviation: - Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-04-10 Completed Date: 2009-05-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101235661 Medline TA: Curr HIV/AIDS Rep Country: United States |
Other Details:
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Languages: eng Pagination: 63-7 Citation Subset: IM |
Affiliation:
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Division of Infectious Diseases and Geographic Medicine, 300 Pasteur Drive, Room S-101, Stanford, CA 94305-5107, USA. pmgrant@stanford.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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AIDS-Related Opportunistic Infections
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drug therapy*,
etiology Acute Disease Anti-HIV Agents / administration & dosage, therapeutic use Drug Administration Schedule HIV Infections / complications, drug therapy*, immunology Hospitalization Humans |
| Chemical | |
Reg. No./Substance:
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0/Anti-HIV Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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