Document Detail

Initial symptoms of Parkinson's disease with elderly onset.
MedLine Citation:
PMID:  10754369     Owner:  NLM     Status:  MEDLINE    
BACKGROUND/OBJECTIVE: As the incidence of Parkinson's disease (PD) is related to aging, we consider it important to determine how the initial symptoms change with age in order to diagnose early elderly cases of PD accurately. METHODS: 84 patients (age at onset 70.7+/-9.0 years; mean +/-1 SD) were studied to see whether the initial symptoms change according to age. RESULTS: The prevalence of resting tremor was significantly lower in patients of advanced age (p = 0.041). In contrast, the incidence of postural and gait disorders increased significantly with aging (p = 0.032). The prevalences of rigidity and kinetic disorders, which are important clinical features of PD, were not influenced by aging. CONCLUSION: These findings suggest that the cause of PD is not related to the aging process itself, since the prevalences of all symptoms were not influenced by aging. Knowledge of the prevalence of the initial symptoms of PD may contribute to the accurate diagnosis in early and elderly cases.
H Nagayama; M Hamamoto; C Nito; S Takagi; T Miyazaki; Y Katayama
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Gerontology     Volume:  46     ISSN:  0304-324X     ISO Abbreviation:  Gerontology     Publication Date:    2000 May-Jun
Date Detail:
Created Date:  2000-07-14     Completed Date:  2000-07-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7601655     Medline TA:  Gerontology     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  129-32     Citation Subset:  IM    
Copyright Information:
Copyright 2000 S. Karger AG, Basel.
Department of Neurology, Tokyo Metropolitan Tama Geriatric Hospital, Tokyo, Japan.
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MeSH Terms
Age Distribution
Age of Onset
Aged, 80 and over
Disease Progression
Gait Disorders, Neurologic / epidemiology
Middle Aged
Parkinson Disease / diagnosis,  epidemiology*,  physiopathology*
Risk Assessment
Sensitivity and Specificity
Sex Distribution
Statistics, Nonparametric
Tremor / diagnosis,  epidemiology*,  physiopathology*

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