| Initial symptoms of Parkinson's disease with elderly onset. | |
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MedLine Citation:
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PMID: 10754369 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND/OBJECTIVE: As the incidence of Parkinson's disease (PD) is related to aging, we consider it important to determine how the initial symptoms change with age in order to diagnose early elderly cases of PD accurately. METHODS: 84 patients (age at onset 70.7+/-9.0 years; mean +/-1 SD) were studied to see whether the initial symptoms change according to age. RESULTS: The prevalence of resting tremor was significantly lower in patients of advanced age (p = 0.041). In contrast, the incidence of postural and gait disorders increased significantly with aging (p = 0.032). The prevalences of rigidity and kinetic disorders, which are important clinical features of PD, were not influenced by aging. CONCLUSION: These findings suggest that the cause of PD is not related to the aging process itself, since the prevalences of all symptoms were not influenced by aging. Knowledge of the prevalence of the initial symptoms of PD may contribute to the accurate diagnosis in early and elderly cases. |
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Authors:
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H Nagayama; M Hamamoto; C Nito; S Takagi; T Miyazaki; Y Katayama |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Gerontology Volume: 46 ISSN: 0304-324X ISO Abbreviation: Gerontology Publication Date: 2000 May-Jun |
Date Detail:
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Created Date: 2000-07-14 Completed Date: 2000-07-14 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7601655 Medline TA: Gerontology Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 129-32 Citation Subset: IM |
Copyright Information:
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Copyright 2000 S. Karger AG, Basel. |
Affiliation:
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Department of Neurology, Tokyo Metropolitan Tama Geriatric Hospital, Tokyo, Japan. nagaya2@ibm.net |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Age Distribution Age of Onset Aged Aged, 80 and over Aging Comorbidity Disease Progression Female Gait Disorders, Neurologic / epidemiology Humans Male Middle Aged Parkinson Disease / diagnosis, epidemiology*, physiopathology* Prevalence Probability Prognosis Risk Assessment Sensitivity and Specificity Sex Distribution Statistics, Nonparametric Tremor / diagnosis, epidemiology*, physiopathology* |
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