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INITIAL OBSERVATIONS USING A NOVEL "CINE" MAGNETIC RESONANCE IMAGING TECHNIQUE TO DETECT CHANGES IN ABDOMINAL MOTION CAUSED BYENCAPSULATING PERITONEAL SCLEROSIS.
MedLine Citation:
PMID:  21454394     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Encapsulating peritoneal sclerosis (EPS) is an uncommon complication of peritoneal dialysis (PD), with high mortality and morbidity. The peritoneum thickens, dysfunctions, and forms a cocoon that progressively "strangulates" the small intestine, causing malnutrition, ischemia, and infarction. There is as yet no reliable noninvasive means of diagnosis, but recent developments in image analysis of cine magnetic resonance imaging for the recognition of adhesions offers a way forward. We used this protocol before surgery in 3 patients with suspected EPS. Image analysis revealed patterns of abdominal movement that were markedly different from the patterns in healthy volunteers. The volunteers showed marked movement throughout the abdomen; in contrast, movement in EPS patients was restricted to just below the diaphragm. This clear difference provides early "proof of principle" of the approach that we have developed.
Authors:
Benjamin Wright; Angela Summers; John W Fenner; Richard Gillott; Charles Hutchinson; Paul Spencer; Martin E Wilkie; Helen Hurst; Sarah Herrick; Paul E Brenchley; Titus Augustine; Karna Dev Bardhan
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-31
Journal Detail:
Title:  Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis     Volume:  -     ISSN:  0896-8608     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-4-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8904033     Medline TA:  Perit Dial Int     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Radiology and Gastroenterology, Rotherham General Hospital NHS Foundation Trust, Rotherham, United Kingdom.
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