| Initial intensive therapy for multibacillary leprosy patients--in retrospect. | |
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MedLine Citation:
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PMID: 1479875 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We analysed the results of 4845 multibacillary (MB) patients being treated with multidrug treatment (MDT) in the Srikakulam District of Andhra Pradesh, India. Of these, 2309 (47.7%) patients were given an initial 14-day intensive therapy with rifampicin, clofazimine and dapsone, followed by the WHO recommended pulse therapy. The rest of the cases were given only pulse therapy. The improvement in terms of bacteriological clearance and the proportion of cases declared released from treatment (RFT) was found to be significantly higher among patients treated with only pulse therapy. Clinic attendance was found to be better and more regular in patients treated with intensive therapy, and no relapses were seen with either therapy. The implications of these findings on the operational aspects of programme implementation are discussed. |
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Authors:
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P S Rao; B N Reddy; P Krishnamurthy; B R Rao; M V Sastrulu; A Dutta |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Leprosy review Volume: 63 ISSN: 0305-7518 ISO Abbreviation: Lepr Rev Publication Date: 1992 Dec |
Date Detail:
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Created Date: 1993-02-11 Completed Date: 1993-02-11 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0243711 Medline TA: Lepr Rev Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 350-7 Citation Subset: IM |
Affiliation:
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Central Leprosy Teaching and Research Institute, Tamil Nadu, India. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Humans Leprosy / drug therapy*, microbiology Retrospective Studies |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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