Document Detail

Initial in vivo results of the new Medtronic Advantage(TM) bileaflet valve in aortic position and comparison to the SJM.
MedLine Citation:
PMID:  12379409     Owner:  NLM     Status:  MEDLINE    
The present study investigated the Medtronic Advantage (MA) bileaflet valve in an animal model and compared the results to the St. Jude Medical (SJM) valve. Systolic performance and coronary artery flow in different orientations were studied.A rotation device holding either a MA or SJM aortic valve size 23 mm was implanted into eight pigs. Transvalvular pressure gradients and ventricular dimensions were investigated with the valves in different orientations. Coronary artery flow was measured at normal and high cardiac output. Orientation significantly influenced the hemodynamic performance of both valves. The best results for both valves were obtained with one orifice proximal to the right cusp. Pressure gradients and ventricular dimensions of the MA corresponded to the SJM. Coronary artery flow was higher for the MA. The systolic performance of the new MA bileaflet valve was similar to the SJM. During diastole, the MA showed significantly higher LAD coronary flow.
Peter Kleine; Armin A Klesius; Mirella Scherer; Ulf Abdel-Rahman; Anton Moritz
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Cardiovascular surgery (London, England)     Volume:  10     ISSN:  0967-2109     ISO Abbreviation:  Cardiovasc Surg     Publication Date:  2002 Oct 
Date Detail:
Created Date:  2002-10-15     Completed Date:  2003-02-24     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  9308765     Medline TA:  Cardiovasc Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  494-9     Citation Subset:  IM    
Department of Thoracic and Cardiovascular Surgery, Johann-Wolfgang-Goethe University, Frankfurt/Main, Germany.
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MeSH Terms
Aortic Valve / physiopathology,  surgery*
Blood Pressure
Coronary Circulation
Coronary Vessels / physiopathology
Heart Valve Prosthesis*
Heart Valve Prosthesis Implantation
Prosthesis Design

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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