Document Detail

Initial exploration of Ti-Ta, Ti-Ta-Ir and Ti-Ir alloys: Candidate materials for coronary stents.
MedLine Citation:
PMID:  18396116     Owner:  NLM     Status:  MEDLINE    
The objective of this study was to explore titanium alloys with increased elastic modulus and improved radiopacity, with a view to utilizing titanium in balloon-expandable coronary stents. Ti-50Ta, Ti-45Ta-5Ir and Ti-17Ir alloys were prepared using arc-melting techniques. Microstructural and tensile properties were evaluated in solution-treated conditions for each alloy, and also in aged conditions for the Ti-17Ir. An elastic modulus of 128GPa was recorded for the Ti-17Ir alloy and this high value is attributed to the stiff Ti(3)Ir phase present in the eutectoid structure observed. The mechanical properties recorded, in addition to improved radiopacity, make the Ti-17Ir alloy more suitable for stent applications than commercially available titanium materials. Corrosion resistance and biocompatibility have not been assessed but the noble characteristics of iridium suggest that these aspects will be acceptable.
Barry O'Brien; Jon Stinson; William Carroll
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Publication Detail:
Type:  Journal Article     Date:  2008-03-20
Journal Detail:
Title:  Acta biomaterialia     Volume:  4     ISSN:  1742-7061     ISO Abbreviation:  -     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-08-11     Completed Date:  2008-11-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101233144     Medline TA:  Acta Biomater     Country:  England    
Other Details:
Languages:  eng     Pagination:  1553-9     Citation Subset:  IM    
National Centre for Biomedical Engineering Science, National University of Ireland Galway, Ireland.
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MeSH Terms
Biocompatible Materials / chemistry*
Blood Vessel Prosthesis*
Body Fluids / chemistry*
Coronary Vessels / surgery*
Iridium / chemistry*
Materials Testing
Pilot Projects
Surface Properties
Tensile Strength
Titanium / chemistry*
Reg. No./Substance:
0/Biocompatible Materials; 7439-88-5/Iridium; 7440-32-6/Titanium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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