| Initial experience with laparoscopic ultrasound-guided radiofrequency thermal ablation of hepatic tumours. | |
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MedLine Citation:
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PMID: 10376460 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND STUDY AIMS: Radiofrequency (RF) thermal ablation has been applied almost exclusively through the percutaneous approach under radiological/external ultrasound guidance. We have embarked on a programme of laparoscopic ultrasound-guided RF ablation of hepatic tumours in view of the potential advantages of this approach, i. e. reduced heat sink effect, greater precision and improved assessment of the thermal ablative zone. PATIENTS AND METHODS: RF thermal ablation using the Zomed International generator and multielectrode probes in two patients with hepatoma arising on a background of cirrhosis and in eight patients with multiple deposits from primary colorectal cancer. RESULTS: Total ablation was performed in two patients with hepatoma and 7/8 patients with secondary deposits. Total ablation with a minimum of 0.5-cm margin was achieved in 32 lesions. No complications were encountered postoperatively and all patients were discharged within 2 days of the intervention. One patient in whom thermal ablation was not completed has since died of progressive disease, eight appear to be free of tumour (follow-up 6-20 months) but one patient has developed further secondary hepatic deposits. CONCLUSIONS: The initial experience with laparoscopic ultrasound-guided RF ablation of hepatic tumours indicates its safety and therapeutic potential in patients with inoperable hepatic tumours. |
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Authors:
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A Cuschieri; J Bracken; L Boni |
Publication Detail:
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Type: Clinical Trial; Clinical Trial, Phase II; Journal Article |
Journal Detail:
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Title: Endoscopy Volume: 31 ISSN: 0013-726X ISO Abbreviation: Endoscopy Publication Date: 1999 May |
Date Detail:
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Created Date: 1999-08-23 Completed Date: 1999-08-23 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0215166 Medline TA: Endoscopy Country: GERMANY |
Other Details:
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Languages: eng Pagination: 318-21 Citation Subset: IM |
Affiliation:
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Dept. of Surgery, Ninewells Hospital and Medical School, University of Dundee, Scotland. a.cuschieri@dundee.ac.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Carcinoma, Hepatocellular / secondary, surgery*, ultrasonography Catheter Ablation / methods* Colorectal Neoplasms / pathology Humans Laparoscopy / methods* Liver Neoplasms / secondary, surgery*, ultrasonography Middle Aged Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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