Document Detail

Initial experience with fenoldopam in children.
MedLine Citation:
PMID:  11329109     Owner:  NLM     Status:  MEDLINE    
Fenoldopam is a direct-acting vasodilator that acts at the postsynaptic dopamine 1 receptors in renal, coronary, cerebral, and splanchnic vasculature resulting in arterial dilation and a lowering of the mean arterial pressure (MAP). Preliminary evidence suggests its efficacy in the treatment of hypertensive urgencies and emergencies in adults. We present four children in whom fenoldopam was used to control MAP in various clinical scenarios, including hypertensive emergencies and urgencies, intraoperative reduction of MAP for controlled hypotension, and control of MAP during extracorporeal membrane oxygenation. The possible applications of fenoldopam and suggested dosing regimens in children are reviewed.
L M Strauser; R D Pruitt; J D Tobias
Related Documents :
25282139 - Characterization of the withdrawal phase in a swine controlled intestinal donation afte...
24350329 - Negative area compressibility in silver(i) tricyanomethanide.
16619749 - Relationship between waist circumference and blood pressure among the population in bag...
8872829 - Obesity-related hypertension: its physiological basis and pharmacological approaches to...
1489219 - Do maternal and intrauterine factors influence blood pressure in childhood?
1534169 - Left ventricular hypertrophy. its relationship to obesity and hypertension.
8191329 - Do high fetal catecholamine levels affect heart rate variability and meconium passage d...
23905599 - Carotid baroreceptor stimulation: a promising approach for the management of resistant ...
7966779 - Neurogenic modulation of micturition: the relation between stimulation intensity and th...
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  American journal of therapeutics     Volume:  6     ISSN:  1075-2765     ISO Abbreviation:  Am J Ther     Publication Date:  1999 Sep 
Date Detail:
Created Date:  2001-04-30     Completed Date:  2001-06-28     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9441347     Medline TA:  Am J Ther     Country:  United States    
Other Details:
Languages:  eng     Pagination:  283-8     Citation Subset:  IM    
Department of Child Health, Division of Pediatric Critical Care/Pediatric Anesthesiology, University of Missouri, Columbia, MI 65212, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Age Factors
Antihypertensive Agents / pharmacology,  therapeutic use*
Body Weight
Brain Neoplasms / surgery
Dopamine Agonists / pharmacology,  therapeutic use*
Fenoldopam / pharmacology,  therapeutic use*
Hypertension / drug therapy*,  etiology
Infusions, Intravenous
Intraoperative Complications / drug therapy,  etiology
Medulloblastoma / surgery
Near Drowning / complications
Postoperative Complications / drug therapy,  etiology
Scoliosis / surgery
Vasodilator Agents / pharmacology,  therapeutic use*
Reg. No./Substance:
0/Antihypertensive Agents; 0/Dopamine Agonists; 0/Vasodilator Agents; 67227-56-9/Fenoldopam

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Pediatric research: coming of age in the new millennium.
Next Document:  Outcome evaluation of long-term nasal continuous positive airway pressure therapy in obstructive sle...