Document Detail


Initial experience with the new Amplatzer Duct Occluder II.
MedLine Citation:
PMID:  19652254     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Different devices are used for transcatheter occlusion of patent ductus arteriosus (PDA), each with its own limitations and complications. We report our initial single-center experience with the new Amplatzer Duct Occluder II (ADO II), which has been designed to address some of these issues. METHODS: From April until October 2008, 10 consecutive patients with PDA (minimal diameter > or = 2 mm) were enrolled for intention-to-treat with ADO II. The median age was 10.2 years (7 months to 51.4 years); the median weight was 35.5 kg (6.3-70 kg). RESULTS: ADO II implantation was attempted in 10/10 patients. The mean PDA diameter was 3.1 mm (+/- 1.0 mm), and the mean device waist diameter was 4.0 mm (+/- 1.3 mm). In 1 patient, the ADO II encroached upon the left pulmonary artery, hence it was changed to an Amplatzer Duct Occluder I. In another patient, the shape and size of the duct necessitated the use of a Cook detachable coil. Complete angiographic closure was achieved in 8/8 ADO II implantations (100%) and in the patient with the coil. In the patient with an ADO I, complete echocardiographic closure was demonstrated at 24 hours. No device embolization or complications related to implantation occurred. CONCLUSIONS: This initial experience demonstrates the feasibility and efficacy of the ADO II to occlude PDA with a minimum diameter > or = 2 mm. It is especially useful in smaller children with larger duct diameters. Longer-term follow up in a larger cohort of patients is required to establish safety and long-term results.
Authors:
Jaspal Dua; Massimo Chessa; Luciane Piazza; Diana Negura; Angelo Micheletti; Claudio Bussadori; Gianfranco Butera; Mario Carminati
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of invasive cardiology     Volume:  21     ISSN:  1557-2501     ISO Abbreviation:  J Invasive Cardiol     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-08-04     Completed Date:  2010-01-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8917477     Medline TA:  J Invasive Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  401-5     Citation Subset:  IM    
Affiliation:
Policlinico San Donato, Department of Paediatric Cardiology and Adult with Congenital Heart Defeca, via Morandi 30, San Donato Milanese, Milan, 20097, Italy. jaspaldua@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Child
Child, Preschool
Ductus Arteriosus, Patent / therapy*,  ultrasonography
Echocardiography
Equipment Design* / adverse effects
Feasibility Studies
Follow-Up Studies
Heart Catheterization / instrumentation*,  methods
Humans
Infant
Middle Aged
Retrospective Studies
Septal Occluder Device* / adverse effects
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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