Document Detail

Initial clinical experience with a novel visualization and virtual electrode radiofrequency ablation catheter to treat atrial flutter.
MedLine Citation:
PMID:  21056697     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: Linear ablation lesions are used to treat a variety of cardiac arrhythmias. However, successful long-term outcome is hampered by both the uncertainty of catheter-tissue contact for any individual lesion and the difficulty in ensuring point-to-point lesion contiguity.
OBJECTIVE: A novel virtual electrode radiofrequency ablation catheter equipped with an endoscope to directly visualize the target tissue was used to ensure tissue contact and lesion contiguity along the cavotricuspid isthmus (CTI) to treat typical atrial flutter.
METHODS: In this feasibility study of five patients with drug-resistant CTI-dependent atrial flutter, catheter ablation was performed using the visualization virtual electrode radiofrequency ablation catheter. After standard femoral access, the ablation catheter was advanced to the tricuspid annulus under fluoroscopic and intracardiac echocardiography guidance. In three of five patients, the ablation procedure was performed during atrial flutter; the other two ablations were during coronary sinus pacing.
RESULTS: Conversion to sinus rhythm was noted after the delivery of 12 ± 7 lesions. Bidirectional CTI conduction block was successfully achieved in all patients. Initial, transient CTI block was first observed after delivering 19 ± 13 lesions; ultimately, 34 ± 18 lesions were required to achieve permanent bidirectional CTI block. The mean ablation and procedure times were 72 ± 42 and 151 ± 17 minutes. The mean fluoroscopy times for the ablation alone and the entire procedure were 13 ± 8 and 17 ± 7 minutes, respectively.
CONCLUSIONS: This study introduces the clinical feasibility of a novel paradigm for contiguous linear ablation: virtual electrode ablation under direct endoscopic visualization.
Humera Ahmed; Petr Neuzil; Jan Skoda; Jan Petru; Lucie Sediva; Stepan Kralovec; Vivek Y Reddy
Related Documents :
19563367 - Localization of left atrial ganglionated plexi in patients with atrial fibrillation.
18982437 - Conventional oral anticoagulation may not replace prior transesophageal echocardiograph...
19406267 - Comparison of characteristics and significance of immediate versus early versus no recu...
19476107 - Effect of atrial fibrillation ablation on left atrial contractile function in patients ...
18449037 - Prospective pulmonary function comparison of anterior spinal fusion in adolescent idiop...
21284797 - The role of sacral neuromodulation in double incontinence.
Publication Detail:
Type:  Journal Article     Date:  2010-11-04
Journal Detail:
Title:  Heart rhythm : the official journal of the Heart Rhythm Society     Volume:  8     ISSN:  1556-3871     ISO Abbreviation:  Heart Rhythm     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101200317     Medline TA:  Heart Rhythm     Country:  United States    
Other Details:
Languages:  eng     Pagination:  361-7     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.
Cardiac Arrhythmia Services, Mount Sinai School of Medicine, New York, New York.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Long-term monitoring of infliximab therapy for perianal fistulizing Crohn's disease by using magneti...
Next Document:  Importance of regional specificity of T-wave alternans in assessing risk for cardiovascular mortalit...