| Inhibitory effects of bovine lactoferrin and lactoferricin B on Enterobacter sakazakii. | |
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MedLine Citation:
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PMID: 18432114 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The susceptibility of Enterobacter sakazakii, a food-borne pathogen, to several metal-bound forms of bovine lactoferrin (LF), pepsin-hydrolyzed LF (LF-hyd), and LF-derived peptide lactoferricin B (LFcin B) was tested. MIC and MBC testing revealed that 4 strains of E. sakazakii show susceptibility to apo- and Cu-LF, LF-hyd, and LFcin B, but not to Fe-LF, similarly to Escherichia coli. A growth curve test indicated that E. sakazakii was inhibited in a dose-dependent manner by apo-LF at 0.5 to 8 mg/ml. Even after being heated at 80 degrees C, LF at above 1 mg/ml inhibited the bacterial growth. These results suggest that bovine LF-related compounds may be useful for the inhibition of E. sakazakii in foods. |
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Authors:
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Hiroyuki Wakabayashi; Koji Yamauchi; Mitsunori Takase |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Biocontrol science Volume: 13 ISSN: 1342-4815 ISO Abbreviation: Biocontrol Sci Publication Date: 2008 Mar |
Date Detail:
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Created Date: 2008-04-24 Completed Date: 2008-05-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9712121 Medline TA: Biocontrol Sci Country: Japan |
Other Details:
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Languages: eng Pagination: 29-32 Citation Subset: IM |
Affiliation:
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Food Science & Technology Institute, Morinaga Milk Industry Co., Ltd., Zama, Kanagawa 228-8583, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Bacterial Agents
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pharmacology* Enterobacter sakazakii / drug effects*, growth & development Lactoferrin / pharmacology* Microbial Sensitivity Tests |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/Lactoferrin; 146897-68-9/lactoferricin B |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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