| Inhibitory effect of some triterpenes from cacti on 32Pi-incorporation into phospholipids of HeLa cells promoted by 12-O-tetradecanoylphorbol-13-acetate. | |
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MedLine Citation:
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PMID: 10374243 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Seventeen triterpenes isolated from cacti and the 10 derivatives were examined for the inhibition of tumor promoter-induced effects in vitro, such as stimulation of 32Pi-incorporation into phospholipids of cultured cells. Betulinic acid (1), cochalic acid (15), erythrodiol (16), oleanolic acid (21) and queretaroic acid (24) inhibited 12-O-tetradecanoylphorbol-13-acetate (TPA) stimulated 32Pi-incorporation into phospholipids of the cultured cells. |
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Authors:
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K Kinoshita; Y Yang; K Koyama; K Takahashi; H Nishino |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Phytomedicine : international journal of phytotherapy and phytopharmacology Volume: 6 ISSN: 0944-7113 ISO Abbreviation: Phytomedicine Publication Date: 1999 May |
Date Detail:
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Created Date: 1999-07-23 Completed Date: 1999-07-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9438794 Medline TA: Phytomedicine Country: GERMANY |
Other Details:
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Languages: eng Pagination: 73-7 Citation Subset: IM |
Affiliation:
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Department of Pharmacognocy and Phytochemistry, Meiji Pharmaceutical University, Tokyo, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Carcinogens / pharmacology* Chick Embryo Hela Cells Humans Phospholipids / metabolism* Phosphorus Radioisotopes / metabolism* Plants / chemistry* Tetradecanoylphorbol Acetate / pharmacology* Triterpenes / pharmacology* |
| Chemical | |
Reg. No./Substance:
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0/Carcinogens; 0/Phospholipids; 0/Phosphorus Radioisotopes; 0/Triterpenes; 16561-29-8/Tetradecanoylphorbol Acetate |
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