Document Detail


Inhibitory effect of asiatic acid on acetylcholinesterase, excitatory post synapticpotential and locomotor activity.
MedLine Citation:
PMID:  22112723     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The asiatic acid, a triterpenoids isolated from Centella asiatica was used to delineate its inhibitory effect on acetylcholinesterase (AChE) properties, excitatory post synaptic potential (EPSP) and locomotor activity. This study is consistent with asiatic acid having an effect on AChE, a selective GABA(B) receptor agonist and no sedative effect on locomotor.
Authors:
M N Nasir; J Abdullah; M Habsah; R I Ghani; G Rammes
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-11-21
Journal Detail:
Title:  Phytomedicine : international journal of phytotherapy and phytopharmacology     Volume:  -     ISSN:  1618-095X     ISO Abbreviation:  -     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9438794     Medline TA:  Phytomedicine     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier GmbH. All rights reserved.
Affiliation:
Department of Neurosciences, School of Medical Sciences, Universiti Sains Malaysia, Malaysia; Faculty of Medicine and Health Sciences, Universiti Sultan Zainal Abidin, Malaysia.
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