Document Detail


Inhibitory Effect of Dexamethasone on Arginine-Vasopressin Release Induced by Physical Exercise in Man.
MedLine Citation:
PMID:  21224738     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
To establish whether glucocorticoids inhibit the arginine-vasopressin (AVP) response to physical exercise, 10 healthy men underwent bicycle ergometer tests until exhaustion (exercise control test, exercise plus dexamethasone [2 or 4 mg in an intravenous bolus]). Physiological and biochemical variables were similar in all tests. Pretreatment with dexamethasone (2 or 4 mg) partially but significantly decreased the AVP response induced by physical exercise. Our results demonstrate a partial inhibition induced by glucocorticoids of AVP neurosecretion during cycle ergometer tests.
Authors:
Vittorio Coiro; Riccardo Volpi; Elio Volta; Andrea Melani; Maria Ludovica Maffei; Paolo Chiodera
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-1-8
Journal Detail:
Title:  Journal of investigative medicine : the official publication of the American Federation for Clinical Research     Volume:  -     ISSN:  1708-8267     ISO Abbreviation:  -     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-1-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9501229     Medline TA:  J Investig Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
From the *Department of Internal Medicine and Biomedical Sciences and †Graduate School in Physical Exercise and Sport Sciences, University of Parma; and ‡Department of Cardiology, Hospital of Parma, Parma, Italy.
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