Document Detail


Inhibitors of stone formation in hypercalciuric children with and without stone disease.
MedLine Citation:
PMID:  1499630     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The extretion of two inhibitors of urinary stone formation (citrate, magnesium) was evaluated in 71 hypercalciuric children and 50 controls. Patients were classified into two groups: 42 nonstone former (NSF), 22 boys and 20 girls, 3-14 years old, and 29 stone formers (SF), 18 boys and 11 girls, 2.5-18 years old. Our study was unable to show significant differences in magnesium and citrate urinary outputs between controls and patient groups. The Mg/Ca ratio was found significantly lower in hypercalcuric children than in controls (p less than 0.001), but not between NSF and SF patients. Our data demonstrated that both NSF and SF groups had a significantly lower citrate/Ca ratio than controls (p less than 0.001), also it was lower in SF than in NSF (p less than 0.05). We found no significant difference in citrate excretion between boys and girls neither in patients nor in controls.
Authors:
A al-Qadreh; H Athanasopoulou; I Voskaki
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  European urology     Volume:  21     ISSN:  0302-2838     ISO Abbreviation:  Eur. Urol.     Publication Date:  1992  
Date Detail:
Created Date:  1992-09-17     Completed Date:  1992-09-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7512719     Medline TA:  Eur Urol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  227-30     Citation Subset:  IM    
Affiliation:
Institute of Child Health, Ag. Sophia Children's Hospital, Athens, Greece.
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MeSH Terms
Descriptor/Qualifier:
Calcium / urine*
Causality
Child
Citrates / urine*
Citric Acid
Female
Humans
Kidney Calculi / epidemiology,  urine*
Magnesium / urine*
Male
Chemical
Reg. No./Substance:
0/Citrates; 7439-95-4/Magnesium; 7440-70-2/Calcium; 77-92-9/Citric Acid

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