| An Inhibitor of Glutathione S-Transferase Omega 1 that Selectively Targets Apoptotic Cells. | |
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MedLine Citation:
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PMID: 22777685 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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On (cell) suicide watch: The increased permeability of apoptotic cells was used to identify a peptide-based, covalent inhibitor (NJP2) for glutathione S-transferase omega (GSTO1) that is highly selective for apoptotic cells, with no inhibition of healthy cells. This apoptosis-specific peptide could also be used for imaging programmed cell death. |
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Authors:
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Nicholas J Pace; Daniel R Pimental; Eranthie Weerapana |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-7-6 |
Journal Detail:
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Title: Angewandte Chemie (International ed. in English) Volume: - ISSN: 1521-3773 ISO Abbreviation: - Publication Date: 2012 Jul |
Date Detail:
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Created Date: 2012-7-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370543 Medline TA: Angew Chem Int Ed Engl Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
Affiliation:
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Department of Chemistry, Merkert Chemistry Center, Boston College, 2609 Beacon Street, Chestnut Hill, MA 02467 (USA). |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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