Document Detail

An Inhibitor of Glutathione S-Transferase Omega 1 that Selectively Targets Apoptotic Cells.
MedLine Citation:
PMID:  22777685     Owner:  NLM     Status:  Publisher    
On (cell) suicide watch: The increased permeability of apoptotic cells was used to identify a peptide-based, covalent inhibitor (NJP2) for glutathione S-transferase omega (GSTO1) that is highly selective for apoptotic cells, with no inhibition of healthy cells. This apoptosis-specific peptide could also be used for imaging programmed cell death.
Nicholas J Pace; Daniel R Pimental; Eranthie Weerapana
Related Documents :
8775045 - Therapy of gonadal stromal cell testicular tumours.
8912385 - Some characteristics of tumour control probability for heterogeneous tumours.
19576655 - Metastatic potential of lung squamous cell carcinoma associated with hspc300 through it...
10998445 - Profile of epidermal growth factor receptor (egfr) expression in human malignancies: ef...
10448075 - Characterization of myosin v from pc12 cells.
15366015 - Worniu, a snail family zinc-finger protein, is required for brain development in drosop...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-6
Journal Detail:
Title:  Angewandte Chemie (International ed. in English)     Volume:  -     ISSN:  1521-3773     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370543     Medline TA:  Angew Chem Int Ed Engl     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Department of Chemistry, Merkert Chemistry Center, Boston College, 2609 Beacon Street, Chestnut Hill, MA 02467 (USA).
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The severity of mental disorders is linked to interaction among candidate genes.
Next Document:  Antibody nanoparticle dispersions formed with mixtures of crowding molecules retain activity and in ...